Objective: The high global incidence of type 2 diabetes has challenged researchers to establish animal models that resemble the chronic stage observed in type 2 diabetes patients. One such model is induced by neonatal streptozotocin (n-STZ) administration to rat pups at 0, 2, or 5 days after birth. In this study, we assessed Ins-1 gene expression and tissue insulin levels as well as serum conce...

The lipid pattern and levels in diabetic patient are the same as those for subjects with cardiovascular disease. tactic underlying oral hypoglycemic agent is to adjust profile; which can be achieved by herbal therapy. use of herbs formulations attenuation hyperglycemia aid protection against pancreatic damage clinically very important. This study was intended find efficacy Katakakhadiradi Kasha...

Diabetes is a metabolic disorder characterized by persistent high glucose level. Linum usitatissimum (flaxseed) which rich in fibre and essential fatty acid one of the functional foods used management diabetes mellitus. The aim this study to evaluate antidiabetic effect L. usititatissimum seed leaf stem on streptozotocin induced diabetic rats see part more potent diabetes. Thirty (30) albino we...

In present study, the effect of alcoholic extract of Momordica charantia, Aegle marmelos and Eugenia jambolana was studied on serum glutamic oxaloacetate transminase and serum glutamic pyruvate transminase activities and on serum urea, total protein and albumin concentrations of streptozotocin diabetic rats. Diabetes in rats was induced by single dose of streptozotocin (30 mg/kg i. p.). On conf...

Diabetes is a life-threatening disease, and currently available synthetic medicines for treating diabetes are associated with various side effects. Therefore, there an unmet need to develop herbal remedies against as alternative medicines. Although local healers use the roots of Spermadicyton suaveolens (SS) manage diabetes, negligible research validate its antidiabetic properties. The present ...

The cytokines IFN-?, interleukin IL-1?, and TNF-? each up regulate the expression of major histocompatibility complex (MHC) are therefore considered as inflammatory markers. present study aimed to measure serum levels in mice after induction diabetes with streptozotocin correlate their lipid glycaemic profiles. included 40 Swiss Albino (20 males 20 females), half male female groups were made di...

The effects of streptozotocin treatment on parathyroid water-clear cells in golden hamsters were investigated. In the cytoplasm of the water-clear cells, lipid droplets were increased as compared to that of the control animals. This finding suggests that treatment of streptozotocin affects functional activity in the parathyroid water-clear cells of the golden hamsters.

Indigenous plants such as Ocimum Sancium, Aegle marmelos, Azadiracta indica, and Murraya koenigii decreased the blood sugar of streptozotocin diabetic rabbits. The most effective drug Aegle marmelos in different solvents showed different rate of hypoglycemic action. On feeding streptozotocin to diabetic rabbits for a period of 3 months aegle marmelos showed remarkable hypoglycemic action.

Treatment of Diabetes Mellitus (DM) is generally through optimizing a balanced diet. Soybeans and sweet potatoes have good antioxidants can be developed as healthy foods for people with diabetes. are processed into Soy-yoghurt. This study aims to determine the potential soy yogurt an antidiabetic in experimental animals, Rattus norvegicus induced by hyperglycemia, using Streptozotocin. used exp...

BACKGROUND: Stevia rebaudiana Bertoni has been used for the treatment of diabetes in, for example, Brazil, although a positive effect on antidiabetic and its complications has not been unequivocally demonstrated. This herb also has numerous therapeutic properties which have been proven safe and effective over hundreds of years. Streptozotocin is a potential source of oxidative stress that induc...