AMA Kuran P, Platos E, Mizerska-Wasiak M, Pańczyk-Tomaszewska M. A rare cause of steroid-resistant nephrotic syndrome – a case report. Central European Journal Immunology. 2023. doi:10.5114/ceji.2023.127534. APA Kuran, P., Platos, E., Mizerska-Wasiak, M., & Pańczyk-Tomaszewska, (2023). https://doi.org/10.5114/ceji.2023.127534 Chicago Paulina, Emilia Małgorzata and Pańczyk-Tomaszewska. "A report...

We present a patient with steroid-resistant nephrotic syndrome due to focal segmental glomerulosclerosis along with smoldering multiple myeloma. While investigating the cause of proteinuria, a monoclonal gammopathy with a negative kidney biopsy for myeloma-related pathology was discovered.

Children who suffer from steroid-resistant nephrotic syndrome (SRNS) require aggressive treatment to achieve remission. When intravenous high-dose methylprednisolone fails, calcineurin inhibitors, such as cyclosporine and tacrolimus, are used as the first line of treatment. A significant number of patients with SRNS progress to end-stage renal disease if remission is not achieved. For these chi...