Apoptosis and underlying mechanisms were evaluated in human umbilical vein endothelial cells (HUVECs), in target tissues of late diabetic vascular complications [human aortic endothelial cells (HAECs) and human retinal endothelial cells (HRECs)], and in endothelial progenitor cells (EPCs) exposed to FFAs, which are elevated in obesity and diabetes. Saturated stearic acid concentration dependent...

BACKGROUND/AIMS Free fatty acids (FFAs) are implicated in diverse signal transduction pathways. The present study investigated the effects of the saturated FFA stearic acid on protein tyrosine phosphatase 1B (PTP1B) activity, Akt activity, and glucose uptake into cells relevant to insulin signal. METHODS PTP1B activity was assayed under the cell-free conditions. Phosphorylation of insulin rec...

Introduction: Dental and oral health has an effect on general health. Orodental disease can be considered asIntroduction: as a major public problem. Tulasi (Ocimum sanctum L.) been acknowledged for their beter remedial value minimal side effects. Therefore, the purpose of writing this article is to review articles with theme uses nutraceutical leaf extract orodental Review: contains good nutrac...

Gel-filtered human platelets were stimulated with 5i.u. of thrombin/ml for times up to 1 min. The fatty acid composition of inositol-containing phospholipids, phosphatidic acid and diacylglycerol was determined by g.l.c. in control and thrombin-stimulated platelet suspensions. Inositol phospholipids were found to have similar proportions of stearic and arachidonic acids, the sum of these repres...

Background and objectives: Amygdalus with a number of endemic species grow vastly in Iran. Edible sweet almond (A. communis), is cultivated in many countries due to its pharmaceutical, nutritional and cosmetic importance; while almond oil which is rich in oleic acid is known for its economic interest. In the present study, the amount and constituents of oil of six Amygdalu...

The kinetics of stearic acid, SA, removal by photocatalytic films are modelled using a log-normal distribution in surface reactivity, which shows that as the ρ, increases, so too does apparent order reaction, m, observed variation SA concentration, [SA], versus irradiation time, t. model is used to fit [SA] vs. t profiles exhibited three very different TiO2 films, namely Activ™ self-cleaning gl...

Various nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (SLNs). Due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. Different strategies have been employed to overcome this problem. In this direction, the present study introduces erodible in-situ forming gel systems as poten...

The lipids were extracted from the winged bean (Psophocarpus tetragonolobus) seed with water-saturated n-butanol. Lipids were separated into groups by preparative TLC on silica gel G. The amount of each lipid type was determined by analysis of the fatty acid constituents in each lipid type. Glyceride was the major lipid accounting for 89.6% of the total, followed by an unknown lipid 4%, free fa...