Xamoterol, a partial β(1)-adrenergic receptor agonist, has been reported to impair the retrieval of hippocampus-dependent spatial reference memory in rats. In contrast, xamoterol restores memory retrieval in gene-targeted mice lacking norepinephrine (NE) and in a transgenic mouse model of Down syndrome in which NE levels are reduced. Restoration of retrieval by xamoterol in these two models com...

Reconsolidation is a putative neuronal process in which the retrieval of a previously consolidated memory returns it to a labile state that is once again subject to stabilization. This study explored the idea that reconsolidation occurs in spatial memory when animals retrieve memory under circumstances in which new memory encoding is likely to occur. Control studies confirmed that intrahippocam...

Current associative theories of contingency learning assume that inhibitory learning plays a part in the interference between outcomes. However, it is unclear whether this inhibitory learning results in the inhibition of the outcome representation or whether it simply counteracts previous excitatory learning so that the outcome representation is neither activated nor inhibited. Additionally, th...

Incorporating syntactic features in a retrieval model has had very limited success in the past, with the exception of term dependencies. This paper presents a new term dependency modeling approach based on a dependency parsing technique used for both queries and documents. Our model is inspired by a quasi-synchronous stochastic process for machine translation [21]. It describes four different t...

Episodic memory encodes the unique contexts of events so that people can remember the details of an experience when cued by only a subset of event features (Tulving, 1972). In humans, the hippocampus is crucial for this kind of memory (Scoville and Milner, 1957; Vargha-Khadem et al., 1997). The present study tested whether the hippocampus was required for nonspatial, context-dependent memory re...

In this research, an automatic control system is designed for landing of a small helicopter on a 4 DOF moving platform. The platform has three translational and one directional degree of freedom. The controller design approach is based on development of helicopter nonlinear dynamic model into the SDC (State Dependent Coefficient) form and real time solving of state dependent Riccati equation (S...

Human neuroimaging studies have suggested that subregions of the medial and lateral parietal cortex form key nodes of a larger brain network supporting episodic memory retrieval. To explore the electrophysiological correlates of functional connectivity between these subregions, we recorded simultaneously from medial and lateral parietal cortex using intracranial electrodes in three human subjec...

This paper addresses the issue of devising a new document prior for the language modeling (LM) approach for Information Retrieval. The prior is based on term statistics, derived in a probabilistic fashion and portrays a novel way of considering document length. Furthermore, we developed a new way of combining document length priors with the query likelihood estimation based on the risk of accep...