In this paper, a new approach is proposed for stress state - dependent flow localization in bifurcation failure model bounded through ductile damage in dynamically loaded sheets. Onset of localized necking is considered in phenomenological way for different strain rates to draw the forming limit diagram (FLD). Using a strain metal hardening exponent in the Vertex theory related to the strain ra...

Deformation-induced martensitic transformation as the basis of a hardening process is dependent, among others, on stress state. In applications such cryogenic cutting, where hardened subsurface can be produced in metastable austenitic steels, different states exist. Furthermore, cutting typically occurs at high strain rates greater than 103s?1. order to gain deeper insight into behavior steel (...

Cardiac sodium channels are integral membrane proteins whose structure is not known at atomic level yet and their molecular kinetics is still being studied through mathematical modeling. This study has focused on adapting an existing model of cardiac Na channel to analyze molecular kinetics of channels at 9-37°C. Irvine et al developed a Markov model for Na channel using Neuronal Network Model ...

Cardiac sodium channels are integral membrane proteins whose structure is not known at atomic level yet and their molecular kinetics is still being studied through mathematical modeling. This study has focused on adapting an existing model of cardiac Na channel to analyze molecular kinetics of channels at 9-37°C. Irvine et al developed a Markov model for Na channel using Neuronal Network Model ...

These experiments examined the effects of pre-test intra dorsal hippocampus (intra-CA1) administration of GABAA receptor agonist and antagonist, muscimol and bicuculline respectively, on state-dependent learning induced by lithium. Male NMRI mice were trained in a one-trial step-down inhibitory avoidance task, and immediately after training they received IP injections of either saline (10 mL/kg...

morphine’s effects on learning and memory processes are well known to depend on synaptic plasticity in the hippocampus. whereas the role of the hippocampus in morphine-induced amnesia and state-dependent learning is established, the biochemical and molecular mechanisms underlying these processes are poorly understood. the present study intended to investigate whether administration of morphine ...