The role of the human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs) as risk factor for spontaneous abortion was investigated in a case-control study in Nairobi, Kenya. Cases (n = 195) were women admitted with clinical signs and symptoms of spontaneous abortion, before 20 weeks of gestation. Patients with induced or clinically septic abortion were excluded. Controls...

Pregnancy is a significant event in a woman’s life, and emotional attachment to the pregnancy and developing baby may begin early in the first trimester. For most women, experiencing a first trimester loss is a difficult and vulnerable time. When it occurs, the grief can be as profound as for any perinatal or other major loss [1]. Spontaneous abortion (a pregnancy that ends spontaneously before...

BACKGROUND Some epidemiologic studies have suggested that the ingestion of caffeine increases the risk of spontaneous abortion, but the results have been inconsistent. METHODS We performed a population-based, case-control study of early spontaneous abortion in Uppsala County, Sweden. The subjects were 562 women who had spontaneous abortion at 6 to 12 completed weeks of gestation (the case pat...

Pregnancy is a significant event in a woman’s life, and emotional attachment to the pregnancy and developing baby may begin early in the first trimester. For most women, experiencing a first trimester loss is a difficult and vulnerable time. When it occurs, the grief can be as profound as for any perinatal or other major loss [1]. Spontaneous abortion (a pregnancy that ends spontaneously before...

BACKGROUND Genetic polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) and transcobalamin (TC) genes influence homocysteine metabolism which in turn may influence the risk of spontaneous abortion. It was hypothesized that there may be a significant interaction between MTHFR and TC genotypes which affects the pathogenesis of spontaneous abortion. METHODS AND RESULTS A total of 76 ...

spontaneous abortion is the most common complication of pregnancy. several lines of evidence indicate that immunologic effector cells may play a role in the pathogenesis of idiopathic repetitive abortions. leukocytes form a substantial proportion of stromal cells in decidua and the endometrial granulated lymphocytes (egl) is the predominant decidual leukocyte population in the first trimester o...

Spontaneous abortion is the most common complication of pregnancy. Immune activation and the subsequent inflammation-induced tissue injury are often observed at the maternal-fetal interface as the final pathological assault in recurrent spontaneous abortion. However, the precise mechanisms responsible for spontaneous abortion involving inflammation are not fully understood. Chemokine CCL28 and ...

OBJECTIVE Few previous studies have examined the role that acute Chlamydia trachomatis lower genital tract infection plays in the development of spontaneous abortion. This study evaluated cervical C. trachomatis infections among 52 women experiencing spontaneous abortion and 59 controls. METHODS Pregnant women at less than 22 weeks of gestation who sought medical care in an emergency departme...

OBJECTIVE To estimate the association between maternal age and fetal death (spontaneous abortion, ectopic pregnancy, stillbirth), taking into account a woman's reproductive history. DESIGN Prospective register linkage study. SUBJECTS All women with a reproductive outcome (live birth, stillbirth, spontaneous abortion leading to admission to hospital, induced abortion, ectopic pregnancy, or h...

BACKGROUND AND OBJECTIVES Ureaplasma urealyticum can colonize women genital tract and be isolated from the amniotic fluid of women with adverse pregnancy outcomes. The association of U. urealyticum with spontaneous abortion remains controversial. The aim of this study was to evaluate the frequency of U. urealyticum infection among pregnant women and its association with spontaneous abortion. ...