Journal:
:hepatitis monthly
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babak behnam cellular and molecular research center, iran university of medical sciences, tehran, ir iran; department of medical genetics and molecular biology, faculty of medicine, iran university of medical sciences, tehran, ir iran; ali-asghar children hospital, iran university of medical sciences, tehran, ir iran
marjan shakiba department of pediatrics, mofid hospital, shahid beheshti university of medical sciences, tehran, ir iran
ali ahani department of genetics and reproduction, avicenna research center, tehran, ir iran
maryam razzaghy azar ali-asghar children hospital, iran university of medical sciences, tehran, ir iran; endocrine and metabolic research center, tehran university of medical sciences, tehran, ir iran; endocrine and metabolic research center, diabetes and metabolic clinic, shahrivar alley, north kargar ave. 1411715851, tehran, ir iran. tel: +98-2166942903, fax: +98-2166421054,
early-onset diabetes, liver dysfunction, growth retardation, spondyloepiphyseal dysplasia, and tendency to skeletal fractures due to osteopenia are characteristics of wolcott-rallison syndrome (wrs). eukaryotic translation initiation factor 2α kinase (eif2ak3) is the only known gene, which is responsible for this rare autosomal recessive disorder. here, we report two siblings a girl and a boy w...