The safety and effectiveness were examined of the spirulina alga on bone metabolism in ovariectomized estrogen-deficient rats and hindlimb-unloaded mice. The dosage range was from an amount equal to that recommended in so-called health foods for humans (0.08 g/kg BW/day) to a 100-fold higher dose. The bone mineral density (BMD) of the whole femur and tibia of ovariectomized rats in the any spir...

Fikobiliprotein terdiri dari fikosianin, allofikosianin, dan fikoeritrin, merupakan komponen bioaktif yang terdapat pada Spirulina platensis (SP), berfungsi sebagai antioksidan antikanker. Metode ekstraksi secara pengadukan freezing-thawing dipilih karena sederhana, paling mudah untuk diterapkan skala industri. Penelitian ini membandingkan kinerja freezing thawing fikobiliprotein (PBP) SP denga...

Background: Microalgae are known to have beneficial effects on health. On the other hand, studies have reported negative effects of diabetes on hematological parameters. Effects of Spirulina platensis (SP) and Chlorella vulgaris (CV) microalgae, singly and combined, on hematological parameters in diabetic rats are not still studied. Thus, the present study was conducted to investigate the effec...

Eutrophication, coupled with ocean acidification and warming, results in an increased concentration of marine algae, severely impacting some regions. Several algae are a rich source protein minerals. Marine bioactive molecules antioxidants, anti-inflammatory, anti-fungal, antimicrobial properties. These properties make them attractive for usage the pharmaceutical industry. This study evaluated ...

Blue-green algae (BGA) have been consumed as food and herbal medicine for centuries. However, safety for their consumption has not been well investigated. This study was undertaken to evaluate in vitro and in vivo toxicity of cultivated Nostoc commune var. sphaeroides Kützing (NO) and Spirulina platensis (SP). Neither NO nor SP contained detectable levels of microcystin (MC)-LA, MC-RR, MC-LW an...

Photosystem I (PS-I) contains a small fraction of chlorophylls (Chls) that absorb at wavelengths longer than the primary electron donor P700. The total number of these long wavelength Chls and their spectral distribution are strongly species dependent. In this contribution we present room temperature time-resolved fluorescence data of five PS-I core complexes that contain different amounts of t...

BACKGROUND/OBJECTIVES Spirulina is a known a functional food related to lipid profiles, immune functions, and antioxidant capacity. Circulating monocyte chemoattractant protein-1 (MCP-1) level is associated with inflammation markers. Single nucleotide polymorphism in the MCP-1 promoter region -2518 have been identified and shown to affect gene transcription. Gene variation may also impact funct...