A survey was conducted to document the results of bracing and spinal fusion for scoliosis associated with osteogenesis imperfecta. Observations were made of 121 patients who underwent treatment by bracing or spinal fusion and who had been treated by 51 orthopaedic surgeons in. 14 countries. The average curve before bracing measured 43 degrees. The braces were ineffective in stopping progression...

surgery on the skeleton frequently requires harvesting of autogenous bone graft from the pelvis, but this procedure often is complicated by problems. the purpose of this retrospective, comparative descriptive study was to compare the efficacy of metal-derived bioactive glass (novabone) versus autogenous iliac crest bone graft in adolescent idiopathic scoliosis surgery. the study was carried out...

A series of 98 patients with juvenile idiopathic scoliosis have been analysed. This showed that between the ages of four and six there was a higher incidence in boys whereas between seven and nine years of age, the proportion of girls was higher. Regardless of sex and age the majority of the curves were convex to the right and the single thoracic curve was the commonest pattern. Spontaneous res...

Much biological experimental data are represented as curves, including measurements of growth, hormone, or enzyme levels, and physical structures. Here we consider the multiple testing problem of comparing two or more nonlinear curves. We model smooth curves of unknown form nonparametrically using penalized splines. We use random effects to model subject-specific deviations from the group-level...

Spinal deformity is a disease mainly suffered by teenagers during their growth stage particularly from element school to middle school. There are many different causes of abnormal spinal curves, but all of them are unknown. The most common type is termed “idiopathic” that show 80% of the spinal deformity. Spinal deformity is a serious disease, mainly suffered by teenagers, especially girl’s stu...

Extensive mechanical loads on the lumbar spine often lead to degenerative damages of spinal structures. In many cases surgical interventions, such as spinal fusion, are unavoidable. An appropriate method for the estimation of the mechanical effects of such interventions to adjacent vertebral segments is the mathematical computer simulation. This paper presents a 3DMultiBodySimulation(MBS-) mode...

distal junctional kyphosis (djk) is a radiographic finding in patients that undergo spinal instrumentation and fusion, since there is an abrupt transition between fixed and mobile spinal segments.the true incidence of djk is variable in literature and seems that has a multifactorial etiology. a consecutive series of 130 patients (mean age 15.6 years) with adolescent idiopathic scoliosis who und...

BACKGROUND Adenosine analogs have been shown to produce antinociception after intrathecal administration. To determine the adenosine receptor subtype involved in spinal antinociception, the effects of selective agonists and an antagonist on the evoked potentials recorded from a neonatal rat spinal cord were studied. The measured potentials are a slow ventral root potential (slow VRP), which is ...

STUDY DESIGN This study investigated the morphology, pathogenesis, and inheritance of idiopathic-like spinal curvature in the guppy syndrome, curveback. OBJECTIVE To determine whether curveback could be applied as a model for the primary factors that contribute to heritable spinal curvature in humans, specifically, the etiopathogenesis of human familial idiopathic scoliosis. SUMMARY OF BACK...