Traumatic spinal cord injury (SCI) is a devastating neurological condition characterized by a constellation of symptoms including paralysis, paraesthesia, pain, cardiovascular, bladder, bowel and sexual dysfunction. Current treatment for SCI involves acute resuscitation, aggressive rehabilitation and symptomatic treatment for complications. Despite the progress in scientific understanding, rege...

BACKGROUND Chronic reflex sympathetic dystrophy (also called the complex regional pain syndrome) is a painful, disabling disorder for which there is no proven treatment. In observational studies, spinal cord stimulation has reduced the pain associated with the disorder. METHODS We performed a randomized trial involving patients who had had reflex sympathetic dystrophy for at least six months....

the prevalence of spinal cord injury (sci) is about 2.5 million in the worldwide and more than 130,000 new injuries reported each year. regeneration in the cns versus the pns is very different from the other tissues and many factors can prevent regeneration in pns and specially cns. previous researches demonstrated that regeneration of cns can inhibit by inhibitory molecules and glial scar. the...

Atstract The possibility of tissue damage in spinal cord stimulation was investigated in a computer modeling study. A decrease of the electrode area in monopolar stimulation resulted in an increase of the current density at the electrode surface. When comparing the modeling results with experimental data from literature, it was concluded that even with a smadl electrode area (0.7 mm3 Lsue damag...