Background: Worldwide, infertility affects about 15% of reproductive-age couples. In many cases, can't be treated, however new treatment options with promising value have been involved in recent clinical trials. The aim this trial was to evaluate the impacts adding coenzyme Q10 (CoQ10) to letrozole on results spermiogram and ...

Abstract Study question How are the semen microbiota compositions of patients with asthenozoospermic and normozoospermic different, According to data from 16S rRNA gene-specific Next-generation sequencing (NGS)? Summary answer Large numbers microbes can be present in seminal fluid, there differences between samples. What is known already Male factor attributable up 50% cases infertility. Most s...

Testicular cancer survival rates have increased to 95%, leading fatherhood becoming a major concern in half of male survivors. Since is not possible predict how chemotherapy (CT) will affect spermatogenesis, sperm cryopreservation before treatment highly recommended. It also unknown whether there an increase the rate chromosomal or epigenetic abnormalities post-CT sperm. Therefore, use fresh st...

Abstract Study question Is there a relationship between the microbiota composition of semen samples used for assisted reproductive technologies (ART) and quality embryos? Summary answer The obligate anaerobes prevalence in was associated with reduced embryo patients astenozoospermia, but no difference found normozoospermic samples. What is known already success ART depends on number factors, in...

Ligneous inflammation is a rare systemic disorder which can affect the conjunctiva, the female genital tract, the upper and lower respiratory system, the gingiva, and the ears [1–3]. The ocular mucosa is the most common site involved. It can be diagnosed by the examination of biopsy material histopathologically. In histopathologic examination, chronic inflammatory changes, which contain amorpho...

Abstract Study question Is Next Generation Sequencing (NGS) an effective diagnostic tool for sperm abnormalities? Summary answer NGS male factor gene panel can be a potent discovering pathogenic variants linked to abnormalities. What is known already Male infertility, responsible half of infertility cases, often shows as absence or decreased count (azoospermia, criptozoospermia oligozoospermia)...

surgery, patient underwent collection of seminal fluid revealing a sperm count of 40 million; the sperm was then cryopreserved to guarantee a future reproductive potential. The serum testosterone level was too low and for this reason, a hormone replacement therapy was set. Three months after injury, the patient reported normal erectile and ejaculatory function. Five months after the injury, spe...

study question: Are temporal trends and values of semen quality parameters in France identifiable in partners of totally infertile women? summary answer: Among a sample of 26 609 partners of totally infertile women undergoing an assisted reproductive technology (ART) procedures in the whole of France over a 17-year period, there was a continuous decrease in semen concentration of about 1.9% per...

STUDY QUESTION Are temporal trends and values of semen quality parameters in France identifiable in partners of totally infertile women? SUMMARY ANSWER Among a sample of 26 609 partners of totally infertile women undergoing an assisted reproductive technology (ART) procedures in the whole of France over a 17-year period, there was a continuous decrease in semen concentration of about 1.9% per...