PURPOSE This work aimed at quantifying the gains in spatial resolution and noise that could be achieved when using resolution modelling based on a multi-ray approach and additionally the Statistical and Heuristic Noise Extraction (SHINE) method in human pinhole single photon emission tomography (PH-SPECT). METHODS PH-SPECT of two line phantoms and one homogeneous cylinder were recorded using ...

The goal of this study was to determine the quantitative accuracy of our OSEM-APDI reconstruction method based on SPECT/CT imaging for Tc-99m, In-111, I-123, and I-131 isotopes. Phantom studies were performed on a SPECT/low-dose multislice CT system (Infinia-Hawkeye-4 slice, GE Healthcare) using clinical acquisition protocols. Two radioactive sources were centrally and peripherally placed insid...

Angulation errors in collimator septa degrade tomographic resolution in SPECT due to mispositioning of events in the projection data. These errors should be small compared to other contributions to SPECT system resolution, such as intrinsic camera and collimator resolution, gantry alignment, and algorithmic smoothing. We describe a radioisotope technique to measure septal angulation errors over...

Today, attenuation corrected SPECT, typically performed using CT or Gadolinium line source based transmission scans, is more and more becoming standard in many medical applications. Moreover, the information about the material density distribution provided by these scans is key for other artifact compensation approaches in advanced SPECT reconstruction. Major drawbacks of these approaches are t...

Objective: A novel multifocal collimator, IQ-SPECT (Siemens) consists of cardio-centric and 3D iterative SPECT reconstruction and makes it possible to perform MPI scans in a short time. The aims are to delineate the normal uptake in thallium-201 (Tl) SPECT in each acquisition method and to compare the distribution between new and conventional protocol, especially in patients with normal imaging...

Quantitation in cardiac positron emission tomography (PET) and single-photon emission computed tomography (SPECT) depends on being able to correct for several physical factors that tend to distort the data. One of the most important of these corrections is the correction for attenuation. For PET, cardiac attenuation correction is a reality, although certain problems remain to be solved. For SPE...

Myocardial perfusion SPECT imaging accounts for well over 90% of all myocardial perfusion imaging performed in the United States today. Although clearly superior to the traditional planar technique in terms of image contrast and consequent diagnostic and prognostic yield, the SPECT approach also involves additional acquisition and processing steps. This article concisely describes the entire te...

Filtered back projection (FBP) method and maximum likelihood expection maximization (OSEM) method are currently used for reconstruction of SPECT images in clinical studies. The aim of this work is to compare the image quality using different reconstruction techniques of a SPECT phantom as applied to bone scintigraphy. The resolution and contrast of the hot spheres were observed using a phantom ...