European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdoma; Kusuma School of Biological Sciences, Indian Institute of Technology, Hauz Khas, New Delhi, Indiab; Department of Biophysics, All India Institute of Medical Sciences, New Delhi, Indiac; National Institute of Pathology, Safdarjung Hospital, New Delhi, Indiad; Departme...

1Department of Electrical Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India 2Department of Electrical Engineering, Stanford University, 232 Packard, 350 Serra Mall, Stanford, CA 94305, USA 3Department of Electronics and Electrical Communication Engineering, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302, India 4Department of Electroni...

Knowledge of simulated genetic effects facilitates interpretation of methodological studies. Genetic interactions for common disorders are likely numerous and weak. Using the 200 replicates of the Genetic Analysis Workshop 16 (GAW16) Problem 3 simulated data, we compared the statistical power to detect weak gene-gene interactions using a haplotype-based test in the UNPHASED software with genoty...

The paper takes a close look at an emerging industry - decentralized finance on the blockchain. goal of this is to compare centralized order book (CLOB)-based exchanges automated market maker (AMM)-based (DEX) and analyze challenges that AMM-based DEXes are facing today using Uniswap as example.

This paper presents the dynamic modelling of a flexible robot manipulator incorporating payload. A planar flexible manipulator incorporating structural damping, hub inertia and payload that moves in the horizontal plane is considered. A dynamic model of the system is developed using a finite element and assumed mode methods (FEM and AMM). In this work will make a comparison between FEM and AMM....

In this study, we proposed a remote authentication model of information appliances (RAMIA). The RAMIA comprised of two basic components, namely user identity security authentication module (UISAM) and authority management module (AMM). The function of UISAM is to authenticate the user by account and password, this module is constructed by hash function and exclusive or (XOR);AMM includes a user...

Cyclic voltammetric surface waves were found for monolayers of Ru(bpy)Z(bpyY+, where bpy’ is 4-methyl4’-(dodecyl-l-thiol)-2,2’-bipyridine, which spontaneously adsorbs onto conducting substrates (indium tin oxide, polycrystalline gold). On polycrystalline gold, the monolayer, probably attached via the thiol functional group, is oxidized in an aqueous oxalate medium to produce electrogenerated ch...

Twenty percent of all childhood deafness is due to mutations in the GJB2 gene (Connexin 26). The aim of our study was to determine the prevalence and spectrum of GJB2 mutations in childhood deafness in Malaysia. We analyzed the GJB2 gene in 51 deaf students from Sekolah Pendidikan Khas Alor Setar, Kedah. Bidirectional sequencing indicates that 25% of our childhood deafness has mutation in their...

Newborn gnotobiotic pigs were inoculated twice perorally (p.o.) (group 1) or intramuscularly (i.m.) (group 2) or three times i.m. (group 3) with inactivated Wa strain human rotavirus and challenged with virulent Wa human rotavirus 20 to 24 days later. To assess correlates of protection, antibody-secreting cells (ASC) were enumerated in intestinal and systemic lymphoid tissues from pigs in each ...

Guidelines for ammonia toxicity in fish are often determined using static exposure tests with immature fish over a 96-h period. These results may not be relevant to aquaculture, hauling or angling tournament scenarios where mature fish can be exposed to ammonia for shorter durations, often following additional stressors such as handling. The current study sought to quantify (1) the impact of am...