We study vehicle routing problems with constraints on the distance traveled by each vehicle or on the number of vehicles. The objective is to minimize the total distance traveled by vehicles. We design constant differential approximation algorithms for some of these problems. In particular we obtain differential bounds: 1 2 for Metric 3VRP,

AIM To evaluate the long-term utilisation of strategic communication as a factor of importance when changing work practices among primary care staff. BACKGROUND In many health care organisations, there is a gap between theory and practice. This gap hinders the provision of optimal evidence-based practice and, in the long term, is unfavourable for patient care. One way of overcoming this barri...

Results of sofosbuvir-based combination therapy for chronic hepatitis C cohort of Indian patients in real-life clinical practice. Sood A1, Midha V2, Mahajan R1, et al. J Gastroenterol Hepatol. 2017 Apr;32(4):894-900. doi: 10.1111/jgh.13628. BACKGROUND AND AIM: The introduction of sofosbuvir has revolutionized the treatment of chronic hepatitis C. This study was planned to observe whether the ef...

O n November 15, 2011, a celebration was held for John S. Fordtran, MD (Figure 1), on the occasion of his 80th birthday. Th e event was initially suggested by Dr. Fordtran’s long-time colleague, Guenter Krejs, MD, who traveled to Dallas from Austria for the event. He was assisted by Charles Richardson, MD, and C. Richard Boland, MD. The celebration began on the evening of November 14, with a di...

This study aims to test the effect of social media marketing activities and brand ambassadors on awareness. The sample used was 245 undergraduate students who were selected using convenience sampling. Data taken a questionnaire analyzed Partial Least Square-Structural Equation Modeling (PLS-SEM). results this indicate that have positive influence

BACKGROUND The purpose of Health Technology Assessment (HTA) is to make the best possible summary of the evidence regarding specific health interventions in order to influence health care and policy decisions. The need for decision makers to find relevant HTA data when it is needed is a barrier to its usefulness. These barriers are highest in rural areas and amongst isolated practitioners. ME...

A threshold of systemic MAGE-A gene expression predicting survival in resected non-small cell lung cancer. Mecklenburg I1, Sienel W2, Schmid S3, Passlick B4, Kufer P5. Clin Cancer Res. 2016 Aug 19. pii: clincanres.0557.2016. [Epub ahead of print] PURPOSE: Quantitative measurement of minimal residual disease (MRD) predicting recurrence in individual cancer patients is available only in very few ...