Background: Solitary fibrous tumour (SFT) is a rare mesenchymal malignancy that lacks robust prognostic and predictive biomarkers. Interferon-stimulated gene 15 (ISG15) ubiquitin-like modifier, associated with progression, poor survival of SFT patients, as previous published by our group. Here, we describe the role ISG15 in biology this tumour. Materials methods: expression was assessed immunoh...