copper (ii) phthalocyanine and 2,9,16,23 tetrakis nitro copper (ii) phthalocyaninehas been synthesized respectively from phthalonitrile and 4-nitro phthalonitrile under solvent-free condition using two different catalystsovernanodimensionalzeolites. 4-nitro phthalonitrile synthesized from phthalimide in three steps. the newly prepared compounds have been characterized by ir, uv-vis, 1hnmr and m...

In an effort to develop new antibacterial drugs, some novel bisindolylmethane derivatives containing Schiff base moieties were prepared and screened for their antibacterial activity. The synthesis of the bisindolylmethane Schiff base derivatives 3-26 was carried out in three steps. First, the nitro group of 3,3'-((4-nitrophenyl)-methylene)bis(1H-indole) (1) was reduced to give the amino substit...

copper (ii) phthalocyanine and 2, 9, 16, 23 tetrakis nitro copper (ii) phthalocyanine has been synthesized respectively from phthalonitrile and 4-nitro phthalonitrile under solvent-free condition using two different catalysts over nanodimensional zeolites. 4-nitro phthalonitrile synthesized from phthaimide in three steps. the newly prepared compounds have been characterized by ir, uv-vis,1h nm...

Currently, the catalytic reduction of nitrobenzene requires more efficient and low-cost catalysts. In this work, a new copper-based metal-organic framework (MOF) was designed by calcination Cu–MOF at 700 °C (denoted as Cu@C). The catalyst showed superior performance toward nitrobenzene, using sodium borohydride (NaBH4) reducing agent, exhibited high conversion (100%) quick reaction time (8 min)...

Solubility and permeability of nitrofurantoin (NITRO) were compared with those its cocrystals containing isoniazid (ISO), bipyridyl (BIP), or phenanthroline (PHE) as coformers, their parent mixtures. NITRO dissolution profiles evaluated via HPLC; we resorted to molecular dynamics (MD) simulations rationalize the experimental data on basis nitrofurantoin–coformers nitrofurantoin–water intermolec...

The consequences of estrogen deficiency on the cardiovascular system have been widely examined in females. The effects of endogenous estrogen deficiency in males are less clear. The aromatase-knockout (ArKO) mouse lacks a functional Cyp19 gene, which encodes aromatase, and is thus incapable of synthesizing endogenous estrogen. In the present study, we examined the effect of lack of endogenous e...

The endothelium regulates vascular tone through release of relaxing or contracting factors, with nitric oxide (NO) being a major endothelium-derived relaxing factor. In the present study, we used a lung explant technique to determine the differential abilities and mechanisms of pulmonary arteries and veins of normal guinea pigs to relax after precontraction. Excised lungs of 15 guinea pigs were...