نتایج جستجو برای: sni model

تعداد نتایج: 2105661  

Journal: :Biological & pharmaceutical bulletin 2015
Dong Wook Lim Jae Goo Kim Taewon Han Sung Keun Jung Eun Yeong Lim Daeseok Han Yun Tai Kim

Ilex paraguariensis, known as "Yerba Mate," is an herb used in a beverage that is widely consumed in southern Latin American countries. Furthermore, it has been traditionally used to treat depression, and as an analgesic to manage both nerve pain and headache. The pain-related experimental evidence regarding the analgesic effects of Mate is unclear. Therefore, this study was designed to investi...

Journal: :JACIC 2004
Ella M. Atkins Min Xue

Runway-independent aircraft have been proposed to increase passenger throughput at crowded urban airports via the use of vertiports or stub runways. Simultaneous noninterfering (SNI) traffic procedures will minimize impact on existing fixed-wing traffic. This paper introduces a SNI trajectory generation algorithm that treats existing fixed-wing traffic corridors as impenetrable obstacles and op...

Journal: :Computers & Security 1991
Ronald Paans Hans de Lange

Auditing complex SNA networks is a scarcely explored area, confronting the reviewers with a number of distinct, though related questions such as: what are the measures for security and internal control integrated in the networks, what are their strengths and weaknesses, how can one verify their effectiveness, and how are the measures impacted by interconnecting networks? From an EDP-auditor's p...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2014
Aquilino Lantero Mónica Tramullas Fuencisla Pílar-Cuellar Elsa Valdizán Rosa Santillán Bernard P Roques María A Hurlé

Transforming growth factor-β1 (TGF-β1) protects against neuroinflammatory events underlying neuropathic pain. TGF-β signaling enhancement is a phenotypic characteristic of mice lacking the TGF-β pseudoreceptor BAMBI (BMP and activin membrane-bound inhibitor), which leads to an increased synaptic release of opioid peptides and to a naloxone-reversible hypoalgesic/antiallodynic phenotype. Herein,...

Journal: :Pain 2007
Magali Millecamps Maria V Centeno Hector H Berra Charles N Rudick Simona Lavarello Tatiana Tkatch A Vania Apkarian

Human brain imaging studies suggest that chronic neuropathic pain has a strong emotional component that is mediated by medial prefrontal cortex (mPFC) activity; in rodents, the mPFC is involved in emotional and cognitive aspects of behavior, including the extinction of Pavlovian fear conditioning. Together, these findings suggest that the cortex may modulate the memory trace of pain. As D-cyclo...

Journal: :Cerebral cortex 2012
Catia Giordano Luigia Cristino Livio Luongo Dario Siniscalco Stefania Petrosino Fabiana Piscitelli Ida Marabese Luisa Gatta Francesca Rossi Roberta Imperatore Enza Palazzo Vito de Novellis Vincenzo Di Marzo Sabatino Maione

During neuropathic pain, caspases are activated in the limbic cortex. We investigated the role of TRPV1 channels and glial caspases in the mouse prelimbic and infralimbic (PL-IL) cortex after spared nerve injury (SNI). Reverse transcriptase-polymerase chain reaction, western blots, and immunfluorescence showed overexpression of several caspases in the PL-IL cortex 7 days postinjury. Caspase-3 r...

2005
Peter Stauvermann

The Dutch economist Roefie Hueting has published since 1969 a long record of books and articles about the Sustainable National Income (SNI). He was one of the first economists who developed the idea of a SNI. The SNI is the present national income minus the abatement costs, which are necessary to preserve the status quo of the environment. Hueting defines the term environmental "sustainability"...

Journal: :Neuroscience letters 2006
A Vania Apkarian Simona Lavarello Anke Randolf Hector H Berra Dante R Chialvo Hugo O Besedovsky Adriana del Rey

We examined mRNA expression of the pro-inflammatory cytokine IL-1beta in the brainstem, thalamus, and prefrontal cortex in two rat models of neuropathic pain. Rats received a neuropathic injury: spared nerve injury (SNI) or chronic constriction injury (CCI), sham injury, or were minimally handled (control). Neuropathic pain-like behavior was monitored by tracking tactile thresholds. SNI-injured...

GhA Hamidi H Manaheji

To study the neuropathic pain mechanism, various behavioral responses of animals in to different neuropathic models were considered. Adult male Sprague-Dawley rats weighing 230-280 g were used. Anesthesia was initially induced with pentobarbital I.P. (50 mg/kg). These models included (1): chronic constriction injury (CCI) by loose ligation of the sciatic nerve (2) Spared nerve injury (SNI) by a...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
Michael Costigan Andrew Moss Alban Latremoliere Caroline Johnston Monica Verma-Gandhu Teri A Herbert Lee Barrett Gary J Brenner Daniel Vardeh Clifford J Woolf Maria Fitzgerald

Partial peripheral nerve injury in adult rats results in neuropathic pain-like hypersensitivity, while that in neonatal rats does not, a phenomenon also observed in humans. We therefore compared gene expression profiles in the dorsal horn of adult and neonatal rats in response to the spared nerve injury (SNI) model of peripheral neuropathic pain. The 148 differentially regulated genes in adult,...

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