immunoproliferative small intestinal disease (ipsid) is the syndrome associated with mediterranean lymphoma (a rare form of non-hodgkin’s lymphoma). many of the patients diagnosed with secretory ipsid have variable level of abnormal immunoglobulins in serum or other bodily fluids, identified as truncated alpha heavy chain globulins. most cases are characterized by a loss of ability to synthesiz...

a 62-year-old woman complaining of severe malabsorption was diagnosed with celiac disease based on the findings of flat, small intestinal mucosa and hla-dq2 positivity, although celiac serology was negative. this diagnosis was questioned due to the lack of clinical and histological improvement after a long period of strict gluten-free diet. the detection of enterocyte autoantibodies guided to t...

celiac disease is characterized by a gluten-induced damage of the small bowel in sensitive individuals that may cause malabsorption. non-intestinal inflammatory diseases may trigger immunologic gluten intolerance in susceptible people and the hcv virus may be considered as a suitable candidate. interferon therapy could precipitate symptom onset in subjects with silent celiac disease. in fact, s...

In order to evaluate the results of abdominal radiation plus chemotherapy in cases with stage II and III of immunoproliferative small intestinal disease in comparison to chemotherapy alone, fifty-one patients referred to Shiraz University of Medical Sciences' affiliated hospitals were studied between 1980 and 1994. Out of them 38 patients who had an abdominal mass were gathered into two gro...

Celiac disease is a gluten-sensitive enteropathy that occurs in genetically predisposed individuals. Patients with the disease must adhere to a strict gluten-free diet. However, not all patients respond promptly to the diet, and some develop symptoms while on the diet. The presence of persistent abdominal pain and blood detected in the stool raise the possibility of complications such as small ...

Intestinal volvulus without malrotation is a rare disease that causes volvulus of the small intestine despite normal intestinal rotation and fixation. We encountered a neonate with this disease who developed early jaundice and was suspected to have a fetal onset. This patient was characterized by early jaundice complicating intestinal volvulus without malrotation and is considered to have exhib...

Celiac disease is a gluten-dependent small intestinal disorder with characteristic, but non-specific histopathological features. A number of disorders may cause similar changes in small intestinal biopsies, but fail to respond to a gluten-free diet. Traditionally, infectious agents, such as giardiasis, were often believed to be responsible, but in many patients with a sprue-like intestinal diso...

Small intestinal anisakiasis is a rare disease that is very difficult to diagnose, and its initial diagnosis is often surgical. However, it is typically a benign disease that resolves with conservative treatment, and unnecessary surgery can be avoided if it is appropriately diagnosed. This case report is an example of small intestinal obstruction caused by anisakiasis that resolved with conserv...

BACKGROUND & AIMS Celiac disease is a chronic inflammatory disease of the small intestine mucosa due to permanent intolerance to dietary gluten. The aim was to elucidate the role of small intestinal epithelial cells in the immunopathology of celiac disease in particular the influence of celiac disease-associated bacteria. METHODS Duodenal biopsies were collected from children with active celi...

Crohn's disease (CD) is an idiopathic inflammatory bowel disease involving the small and/or large intestine. More than 50% of Western CD patients and up to 88% of Asian CD patients may have small intestinal involvement. Video capsule endoscopy (VCE) has a higher diagnostic yield than small bowel barium radiography and computed tomography enterography for the detection of small intestinal involv...