Copper is an essential transition metal with a critical role in the CNS. This requirement is underscored by Menkes disease, a fatal neurodegenerative disorder of childhood resulting from the absence or dysfunction of a copper-transporting P-type ATPase. To elucidate the cell biological mechanisms of copper homeostasis in the CNS, a polyclonal antisera against Menkes ATPase was used in immunoblo...

Cuprous oxide-based antifouling paint is now the most common type in use, especially in the shipping industry. Anti-fouling paints prevent or slow down the growth of organisms attached to the hull, in order to improve a vessel’s performance and durability. However, copper is a scarce resource and never can be retrieved or recycled after leaching into the sea. The need to protect sensitive marin...

Eggers ED, Klein JS, Moore-Dotson JM. Slow changes in Ca cause prolonged release from GABAergic retinal amacrine cells. J Neurophysiol 110: 709–719, 2013. First published May 8, 2013; doi:10.1152/jn.00913.2012.—The timing of neurotransmitter release from neurons can be modulated by many presynaptic mechanisms. The retina uses synaptic ribbons to mediate slow graded glutamate release from bipola...

OWEN, CHARLES A., JR., and JANE B. HAZELRIG. Copper deJi&nc~ and copper toxicify in the rat. Am. J, Physiol. 215(Z) : 334-338. I968.-Changes in metabolism of an intravexmusly injected tracer dose of 64Cu were measured in Sprague-Dawley rats subjected to copper loading, by addition of cupric acetate to the drinking water, or made copper deficient, by use of a milk-powder diet and copper-free wat...

One effort to reduce nitrogen loss is make the fertilizer in a form of slow-release. SRF method can be done conventionally based on centrifugal force. Nitrogen release from UZA fertilizers generally decreased during incubation period. Urea slow-release combination zeolite and humic acid applied soil media rate nitrate release. In this case, it necessary identify effect ready modifying acid. Inc...

(h) Controlled-release glass boluses (35 g) for use in sheep. The bolus contains by weight 13.4% copper. 0.5% cobalt and 0.3% selenium in a soluble glass matrix. (i) Sustained-release rumen bolus (80 g) for cattle. The bolus is composed of a compressed mixture of copper. cobalt. selenium. manganese. zinc. iodine and vitamins A. D and E. The round end of one bolus has been removed to show the 25...