Animals continuously alternate between sleep and wake states throughout their life. The daily organization of sleep and wakefulness is orchestrated by circadian, homeostatic, and motivational processes. Over the last decades, much progress has been made toward determining the neuronal populations involved in sleep/wake regulation. Here, we will discuss how the application of advanced in vivo to...

abstract background: about 79% of pregnant women in the world suffer from sleep disorders. these disorders result from physiological changes during pregnancy, originate from different factors, and can affect pregnant women’s quality of life before, during, and after delivery. this study aimed to investigate the effect of sleep healthy behavior education on the quality of life among pregnant wom...

Circadian Rhythm Disorders: Advanced Phase Sleep Disorder The tendency for elderly patients to spend more time asleep during the day and less time asleep at night raises the possibility that neurological dysfunction of the biologic clock within the suprachiasmatic nucleus of the hypothalamus mediates these changes. Advanced phase sleep disorder is a well-recognized circadian disorder in which p...

background: sleep disorders are common among patients with chronic heart failure (hf), and it can have a significant effect on patients’ daily activities as well as their health. the purpose of this study was to assess sleep quality and its predictors in iranian patients with chronic hf.   methods : this cross-sectional study was conducted on a sample of 200 patients with hf in two hospitals of...

Background: Sleep disturbance is a common complaint of patients undergoing methadone maintenance therapy (MMT). There are limited studies about the effect of different treatments on insomnia due to MMT. In this study, we evaluated the effect of cognitive-behavioral treatment for insomnia (CBTI) on sleep disorders in patients undergoing MMT.Methods: Twenty-two patients with insomnia due to MMT (...

Anticipation is an adaptive process, aiding preparatory responses to potentially threatening events. However, excessive anticipatory responding and associated hyper-reactivity in the amygdala and insula are integral to anxiety disorders. Despite the co-occurrence of sleep disruption and anxiety disorders, the impact of sleep loss on affective anticipatory brain mechanisms, and the interaction w...

To investigate the effects of L-serine intake on human sleep, we conducted two randomized double-blinded crossover studies. In Study 1, healthy subjects who were dissatisfied with their sleep were given L-serine or a placebo 30 min before going to bed. After waking the next morning, subjective sleep quality was rated using the Ogri-Shirakawa-Azumi subjective sleep rating scale. In Study 2, subj...