This experiment was conducted in order to compare the effects of Nigella sativa (NS) and silver sulfadiazine (SSD) cream on healing of burn wounds in rats. Fifty four adult, male Wistar-albino rats were divided into three groups of equal numbers. A burn was generated on the backs of all the rats. The burned areas in the first, second and third groups were covered with daily cold cream (control)...

Deep dermal partial-thickness scalds remain one of the most common types of injuries in childhood. Local treatment of those wounds, alternatively described as IIb degree, is still very controversial. Some authors advise conservative treatment of such wounds, pointing to their ability to self-reepithelialise, which is possible but significantly prolonged. Other investigators postulate operative ...

Burn wound healing involves a series of complex processes which are subject to intensive investigations to improve the outcomes, in particular, the healing time and the quality of the scar. Burn injuries, especially severe ones, are proving to have devastating effects on the affected patients. Stem cells have been recently applied in the field to promote superior healing of the wounds. Not only...

Background Patients presenting with large surface area burns are common in our practice; however, patients with a secondary large burn on pre-existing burn scars and grafts are rare and not reported. Case presentation We report on an unusual case of a patient sustaining a secondary large burn to areas previously injured by a burn from a different mechanism. We discuss the potential implicatio...

Patients with burns and wounds are more likely to contract an infection in the hospital than other patients due loss of protective barrier (skin) immune system disorders that appear these patients, making affected tissues a suitable environment for infection. Hospital is one most severe complications affect significantly increases rates disease death. Burn wound infections frequently harbor bac...

BACKGROUND Burn-induced inflammation leads to impaired immune responses resulting in increased morbidity and mortality. T-cells are central in the immune response and circulating CD4 and CD8 T-cells have been used to evaluate immune status; however, the role of these T-cell subsets in the burn wound is unknown. METHODS Male C57BL/6 mice were subjected to a major 3rd degree scald burn or sham ...

Objective- Our point is to determine if the treatment of the 3rd degree burn wounds makes any difference if sprayed cultured autologous keratinocyte used alone or in combination with Fibrin glue. Design- Animal experimental study. Animals- 30 male Wistar rats. Procedures- Thirty male Wistar rats were selected and their keratinocytes were isolated and cultured from small skin biops...

OBJECTIVE The goal of our study was to find an easy and suitable skin burn model for rabbits, to identify the temperature and contact time to reach a deep 2nd degree burn, and to find the best wound dressing fixation method. MATERIAL AND METHODS We used New Zealand male rabbits as experimental models. On a pilot study, with a copper device heated to temperatures between 43-48 Celsius degrees,...

Thermal injury destroys the physical skin barrier that normally prevents invasion of microorganisms. This and concomitant depression of local and systemic host cellular and humoral immune responses are important factors that contribute to colonization and infection of the burn wound. One of the most common burn wound pathogens is Staphylococcus aureus. Staphylococcus aureus is both a human comm...