Early developmental stages are particularly susceptible to disruption because this is the period for organogenesis. This refers to the 4th to 8th weeks of development. The aim of this study was to determine the pattern of congenital anomalies presenting in tertiary health facilities in Jos and any association between the anomalies. A retrospective study of 200 cases of congenital anomalies that...

Rubinstein-Taybi syndrome (RSTS) can be caused by heterozygous mutations or deletions involving CREBBP or, less commonly, EP300. To date, only 15 patients with EP300 mutations have been clinically described. Frequently reported manifestations in these patients include characteristic facial and limb features, varying degrees of neurocognitive dysfunction, and maternal preeclampsia. Other congeni...

Oral respiration is considered as an important etiological factor of anomalies in the orofacial region. Many studies have shown a correlation between the manner of respiration and antero-posterior relation of the jaws. Aim of this study was to find out the frequency of patients with oral respiration and to determine the reason for oral respiration, as well as to examine different anomalies caus...

Focal musculoskeletal anomalies vary, and can manifest as part of a syndrome or be accompanied by numerous other conditions such as genetic disorders, karyotype abnormalities, central nervous system anomalies and other skeletal anomalies. Isolated focal musculoskeletal anomaly does, however, also occur; its early prenatal diagnosis is important in deciding prenatal care, and also helps in couns...

'Acro-renal syndrome' refers to co-occurrence of congenital renal and limb anomalies. The term acro-renal syndrome was coined by Curran et al. in 1972 though Dieker and Opitz were the first to report this phenomenon in three male patients in 1969. The common limb defects include oligodactyly, ectrodactyly, syndactyly or brachydactyly anomalies of the carpal and tarsal bones and the common renal...

Acro-renal syndrome’ refers to co-occurrence of congenital renal and limb anomalies. The term acro-renal syndrome was coined by Curran et al. in 1972 though Dieker and Opitz were the first to report this phenomenon in three male patients in 1969. The common limb defects include oligodactyly, ectrodactyly, syndactyly or brachydactyly anomalies of the carpal and tarsal bones and the common renal ...

BACKGROUND Limb anomalies rank behind congenital heart disease as the most common birth defects observed in infants. More than 50 classifications for limb anomalies based on morphology and osseous anatomy have been drafted over the past 150 years. The present work aims to provide a concise summary of the most common congenital limb anomalies on a morpho-etiological basis. PATIENTS AND METHODS...

Introduction: A retrospective study of 109 children with anorectal malformations (ARMs) was performed to find the incidence of associated congenital anomalies. Material and methods: 109 consecutive children with ARMs were treated between 1992 and 2008. Analysis included sex, duration of pregnancy, body weight at birth and APGAR score, type of ARM and any associated anomalies. Anorectal malforma...

In this paper, 981 reared juveniles of gilthead seabream (Sparus aurata) were analysed, 721 of which were from a commercial hatchery located in Northern Italy (Venice, Italy) and 260 from the Hellenic Center for Marine Research (Crete, Greece). These individuals were from 4 different egg batches, for a total of 10 different lots. Each egg batch was split into two lots after hatching, and reared...

Background The esophageal atresia (EA) is the most common esophageal congenital anomaly. The aim of this study was to evaluate the predictive factors in the survival of newborns with esophageal atresia. Materials and Methods This was a descriptive-analytic cross-sectional study performed on newborns with esophageal atresia wh...