Drug resistance to tyrosine kinase inhibitor (TKI) is the main obstacle for efficient treatment of epidermal growth factor receptor (EGFR)-mutant lung cancer patients. Here we design a cetuximab-capped mesoporous silica nanoparticle (MP-SiO2 NP) as the drug carrier to specifically target EGFR-mutant lung cancer cells and efficiently release loaded drugs including doxorubicin and gefitinib. This...

We present a facile method for producing anti-fogging (AF) and anti-reflection (AR) coating functionalized photoanodes via one-step SiO2 nanoparticle coating for high performance solid state dye-sensitized solar cells (ssDSSCs). The AF and AR coating functionalized photoanodes are prepared by spin-coating of partially aggregated SiO2 colloidal solution. Poly((1-(4-ethenylphenyl)methyl)-3-butyl-...

Hydrazide chemistry is a powerful technique in glycopeptides enrichment. However, the low density of the monolayer hydrazine groups on the conventional hydrazine-functionalized magnetic nanoparticles limits the efficiency of glycopeptides enrichment. Herein, a novel magnetic nanoparticle grafted with poly(glycidyl methacrylate) (GMA) brushes was fabricated via reversible addition-fragmentation ...

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A simple yet versatile combinatorial method to discover binary metal nanoparticle catalysts was developed. In this method, the nominal thickness of component metals can be independently screened for a wide range by simply setting a mask with a slit above a substrate during sputter-deposition. Using this method, we prepared a catalyst library with Mo (0.2− 4 nm) and Co (0.2− 8 nm) thickness prof...

We present a numerical analysis of surface plasmon waveguides exhibiting both long-range propagation and spatial confinement of light with lateral dimensions of less than 10% of the free-space wavelength. Attention is given to characterizing the dispersion relations, wavelength-dependent propagation, and energy density decay in two-dimensional Ag/SiO2/Ag structures with waveguide thicknesses ra...

We report on the synthesis of nanosized single-crystalline spherical b-Ga2O3 particles (GONP) by thermal annealing of gallium nanoparticles (GaNP), which previously has been prepared under ultrasonication. GONP displayed a spherical morphology and the particle size reflected that of GaNP. The nanoparticles have been confirmed as crystalline b-Ga2O3 by powder X-ray diffraction. The selected area...

THE EFFECT OF CALCINATION TEMPERATURE TO COMPOSITECHARACTERISTICS TiO2SiO2 NANOPARTICLE. Self-cleaning material is a that utilizes the photocatalytic property to degrade organic and inorganic compounds with help of UV light. One materials have good TiO2, causes TiO2 be amphiphilic: becomes hydrophilic when there light hydrophobic no The can improved addition buffer such as SiO2. nanoparticle wa...

Iron containing nanoparticles are found to spontaneously form on hydroxylated SiO2 substrates when immersed in a freshly mixed aqueous solution of FeCl3 and hydroxylamine. Upon calcination, a submonolayer of uniformly distributed iron oxide nanoparticles can be derived and used to catalyze the growth of single-walled carbon nanotubes by chemical vapor deposition. This simple method affords clea...

In this paper, we investigate the impact of modified SiO2 nanoparticles on mechanical properties Polymethyl methacrylate (PMMA) composites through a combination molecular dynamics simulation and experimentation. Our investigation focuses analyzing elastic modulus, bulk shear Cauchy ratio pure PMMA, PMMA/SiO2 composites, PMMA/modified over temperature range 200–400 K. results indicate that, as i...