نتایج جستجو برای: sinonasal

تعداد نتایج: 2893  

Journal: :Archives of otolaryngology--head & neck surgery 2004
Joseph Vandermeer Quan Sha Andrew P Lane Robert P Schleimer

OBJECTIVE To study the expression of important elements of the innate immune responses in human sinonasal tissue to elucidate its potential role in mucosal inflammation. DESIGN We studied human sinonasal tissue from patients with chronic rhinosinusitis and an immortalized epithelial cell line to detect the expression of innate immune effectors and the responses of these cells to stimulation w...

Journal: :The Laryngoscope 2013
Jastin L Antisdel Divya Gumber Janalee Holmes Raj Sindwani

OBJECTIVES/HYPOTHESIS Endoscopic orbital decompression (EnOD) has proven to be safe and effective for the treatment of Graves' orbitopathy; however, complications do occur. Although the literature focuses on orbital complications, sinonasal complications including postobstructive sinusitis, hemorrhage, and cerebrospinal fluid (CSF) leak can also be challenging to manage. This study examines the...

Journal: :Journal of neurological surgery. Part B, Skull base 2016
Liuba Soldatova Raewyn G Campbell Ricardo L Carrau Daniel M Prevedello Paul Wakely Bradley A Otto Leo F Ditzel Filho

Objectives Sinonasal cancers with neuroendocrine features share similar clinical, radiological, and histopathological features; however, these tumors often exhibit varying degrees of aggressive behavior presenting significant treatment challenges. The objective of this study was to report our experience with these rare malignancies and to present a review of current literature. Methods Followin...

2018
Gennaro Ilardi Daniela Russo Silvia Varricchio Giovanni Salzano Giovanni Dell'Aversana Orabona Virginia Napolitano Rosa Maria Di Crescenzo Alessandra Borzillo Francesco Martino Francesco Merolla Massimo Mascolo Stefania Staibano

Human Papilloma Virus (HPV) can play a causative role in the development of sinonasal tract malignancies. In fact, HPV may be the most significant causative agent implicated in sinonasal tumorigenesis and is implicated in as many as 21% of sinonasal carcinomas. To date, there are no definitive, reliable and cost-effective, diagnostic tests approved by the FDA for the unequivocal determination o...

2015
Brian H. Song Daniel Baiyee Jonathan Liang

BACKGROUND Immunoglobulin G4 (IgG4) related sclerosing disease (rSD) is a new disease entity, first described in 2001, that involves autoimmune pancreatitis. Considered a systemic disease with lesions described in multiple organ systems, IgG4-rSD that affects the sinonasal region is rare. Our goal was to highlight the sinonasal presentation of this unique disease and to review previously report...

Journal: :The Laryngoscope 2016
Daniel M Beswick F Christopher Holsinger Michael J Kaplan Nancy J Fischbein Wendy Hara A Dimitrios Colevas Quynh-Thu Le Gerald J Berry Peter H Hwang

OBJECTIVES/HYPOTHESIS Assessment of patients with sinonasal malignancy is challenging due to the low disease incidence and diverse histopathology. The current literature is composed mainly of retrospective studies with heterogeneous cohorts, and the rarity of cases limits our understanding of disease characteristics and treatment outcomes. We describe the development of a prospective, multi-ins...

Journal: :Journal of Korean Medical Science 1994
J. H. Lee S. S. Lee J. H. Park Y. W. Kim M. H. Yang

A high incidence of a T cell phenotype of sinonasal lymphomas in other Asian countries has been associated with a high incidence of Epstein Barr virus (EBV) infection. We analyzed 13 sinonasal and 18 Waldeyer's ring lymphomas for the prevalence of EBV encoded RNA (EBER) using a sensitive and specific in situ hybridization. In addition, we examined the relationship of histologic findings and imm...

Journal: :Cancer epidemiology 2013
Danny R Youlden Susanna M Cramb Susan Peters Sandro V Porceddu Henrik Møller Lin Fritschi Peter D Baade

BACKGROUND This paper reviews international patterns in sinonasal cancer incidence and mortality in light of changes in exposure to known risk factors. Sinonasal tumours are relatively rare, but they have the second highest occupational attributable fraction of all types of cancer, with a well-established link for workers exposed to wood dust. METHODS Data for a variety of countries, mainly i...

Journal: :Journal of clinical pathology 2003
K J Syrjänen

This review updates the evidence that the human papillomavirus (HPV) is involved in the development of benign and malignant sinonasal lesions. Since the early 1980s, when evidence was provided on the possible involvement of HPV in the aetiology of both benign respiratory papillomas and squamous cell carcinomas, a substantial number of studies have explored this issue. To date, 33.3% of sinonasa...

2014
John Gencarelli Ryan Rourke Tracey Ross Denis H. Gravel Bibianna Purgina David Jordan Charles Agbi Shaun J. Kilty

Objective Sinonasal cellular schwannoma represents < 4% of head and neck schwannomas. These benign tumors are typically confined to the nasal cavity or ethmoid sinus. We describe an atypical case of sinonasal cellular schwannoma with diffuse paranasal sinus involvement and both intraorbital and intracranial extension. Results A 62-year-old woman presented with a 6-month history of right orbital...

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