r m c v d C C In the post-genomic era, drug development and diagnostic imaging have become more closely linked in the search for targets. Since the 1940s, nuclear imaging has been based on physiological targets, some more easily saturable than others. Recently, the search for drug targets has been increasingly based on genomics, primarily on genome-wide association studies, an approach used in ...

The solar corona is a tenuous outer atmosphere of the Sun. Its million-degree temperature was discovered spectroscopically in the 1940s, but its origin has been debated since then without complete convergence. Currently there are two classes of models; the wave theory and the microflare/nanoflare theory. Both models have merits and disadvantages, but the essential issues are nearly pinned down....

We are interested in exploring ways in which unconventional modes of computation may provide new directions for future developments in Computer Music. Research into Unconventional Computing (Calude et al. 1998) is aimed at computational paradigms other than the standard von Neumann architecture, which have prevailed in computing since the 1940s. This paper presents an investigation into the fea...

• The Perfect introduces a time interval: the “perfect time span” (PTS). • The Right Boundary (RB) of the PTS is set by Tense. • The Left Boundary (LB) of the PTS may be set by “perfect adverbials”. • The lower predicate (event) is predicated of the PTS, either directly or mediated by various devices, most notably operators associated with the Perfective or Imperfective. • When the predicate ha...

Malignant mesothelioma is a rare tumour strongly associated with asbestos exposure.' It is a notifiable disease in Singapore-voluntarily to the Cancer Registry since 1968 and statutorily under the Factories Act, 1973. Singapore's industrial exposure to asbestos started in the late 1940s with the establishment of a factory engaged in manufacturing asbestos cement products. Asbestos is now being ...