OBJECTIVE The aim of this study was to evaluate the performance of Acute Physiology and Chronic Health Evaluation II (APACHE II), Simplified Acute Physiology Score 3 (SAPS 3), and Acute Physiology and Chronic Health Evaluation IV (APACHE IV) in patients with cancer admitted to intensive care unit (ICU) in a single medical center in China. MATERIALS AND METHODS This is a retrospective observat...

BACKGROUND Physiology-based severity of illness scores are often used for risk adjustment in observational studies of intensive care unit (ICU) outcome. However, the complexity and time constraints of these scoring systems may limit their use in administrative databases. Comorbidity is a main determinant of ICU outcome, and comorbidity scores can be computed based on data from most administrati...

Background Neonatal sepsis is one of the most critical illness in neonates that is responsible for a great proportion of morbidity and mortality in neonates so early diagnosis and identification of high risk cases is a challenging aim of our study. The purpose of this study was to investigate the prognostic value of red cell distribution width (RDW), in neonatal sepsis at the time of admission ...

BACKGROUND Accurate measurement of surgical outcomes, proper evaluation of hospitals and surgeons regardless of case can be performed by mortality prediction models. The aim of this study was to analyze factors affecting mortality, present our clinical experience and patient profile and evaluate different scoring systems in use of these patients. METHODS A retrospective review of one hundred ...

INTRODUCTION Using physiologic scoring systems for identifying high-risk patients for mortality has been considered recently. This study was designed to evaluate the values of Acute Physiology and Chronic Health Evaluation II (APACHE II) and Simplified Acute Physiologic Score (SAPS II) models in prediction of 1-month mortality of critically ill patients. METHODS The present prospective cross ...

OBJECTIVE Argatroban, a direct thrombin inhibitor, was evaluated for anticoagulation in continuous renal replacement therapy (CRRT) in critically ill patients with heparin-induced thrombocytopenia type II and acute renal failure. The investigation focused on predictors for the maintenance doses of argatroban with efficacy and safety of argatroban being secondary outcomes. DESIGN Prospective, ...

PURPOSE This study compared the performance of 3 admission prognostic scores in predicting hospital mortality. MATERIALS AND METHODS Patient admission characteristics and hospital outcome of 9549 patients were recorded prospectively. The discrimination and calibration of the predicted risks of death derived from the Simplified Acute Physiology Score (SAPS III), Admission Mortality Prediction ...

BACKGROUND Outcome prediction scoring systems are increasingly used in intensive care medicine, but most were not developed for use in cardiac surgery patients. We compared the performance of four intensive care outcome prediction scoring systems (Acute Physiology and Chronic Health Evaluation II [APACHE II], Simplified Acute Physiology Score II [SAPS II], Sequential Organ Failure Assessment [S...

BACKGROUND An important, but not well characterized, population receiving intermediate care is that of medical patients admitted directly from the emergency department. OBJECTIVE To characterize emergency medical patients and their outcomes when admitted to an intermediate care unit with clearly defined admission guidelines. METHODS Demographic data, admitting diagnoses, illness severity, c...

Methods The study was designed as a prospective cohort study for patients admitted to the nine intensive care units in the four provincial academic medical centers from September 2013 to February 2014. Validation and comparison were conducted to measure discrimination and calibration with using the area under the receiver operating characteristic curve (AUC) and the Hosmer-Lemeshow test, respec...