Article history: Received on: 19/11/2013 Revised on: 10/12/2013 Accepted on: 05/03/2013 Available online: 27/04/2014 The neuropharmacological activity of different doses (100, 200, 400 mg/kg/p.o.) of petroleum ether (SIP), methanolic (SIM) and aqueous extract (SIA) obtained from Sphaeranthus indicus Linn were studied in mice. Sphaeranthus indicus was evaluated for its effect on motor coordinati...

Background: Therapeutic utilities of doxorubicin (DOX), an anticancer anthracycline antibiotic, are limited by its serious dosedependent toxicity to non-target tissues such as testis. The aim of the present study was to elucidate the potential of simvastatin (SIM), a lipid lowering agent with antioxidant and anti-inflammatory activities, to attenuate DOX-induced spermatotoxicity in male mice. M...

The embryonic neuroepithelium of Drosophila gives rise to the central nervous system. We have studied the mutant phenotype and expression of a gene, single-minded (sim), which is involved in generating a specific region of this neuroepithelium. In sim mutant embryos, a subset of neuronal and nonneuronal precursor cells lying along the midline fail to emerge with the rest of the neuroepithelium....

In this paper we outline an approach to the distributed simulation of agent-based systems using the SIM AGENT toolkit and the High Level Architecture (HLA) simulator interoperability framework. Using a simple Tileworld scenario as an example, we show how the HLA can be used to flexibly distribute a SIM AGENT simulation with different agents being simulated on different machines. We outline the ...

C-Sim is a programming tool for simulation of discrete processes using a method of pseudoparallel processes. It is an extension of C language obtained by including SIMULA-like macros and functions. C-Sim uses a special C-functions and C-macros library. The typical application area of C-Sim is functional validation of distributed, parallel and fault-tolerant systems and programs.

BACKGROUND AND AIM Recently, statins have appeared to have additional benefits beyond their lipid lowering effects, which has led to the interest in the use of this class of drugs outside the realm of cardiovascular disease. Simvastatin (SIM) is a commonly prescribed statin with anti-inflammatory and antioxidant properties. Excessive generation of oxygen-derived free radicals (ODFR) and proinfl...

As the area of Functional Encryption (FE) has grown in importance, the landscape of its security definitions has become increasingly cluttered. Currently prevalent definitions are largely restricted to data privacy, and are broadly categorized as indistinguishability (IND) style or simulation (SIM) style, where the former are known to be insufficient and the latter are known to be unachievable ...

Inhibitors of hydroxymethylglutaryl-CoA reductase or statins have been shown to alleviate endothelial dysfunction. Their effects on constitutive nitric oxide synthase in the central nervous system may hypothetically affect the autonomic balance in sympathoexcitatory states, such as chronic heart failure (CHF). To address this issue, simvastatin (SIM) (0.3, 1.5, or 3 mg. kg-1. day-1 po) was give...

The generalization of Cohen and Glashow’s Very Special Relativity to curved space-times is considered. Gauging the SIM(2) symmetry does not, in general, provide the coupling to the gravitational background. However, locally SIM(2) invariant Lagrangians can always be constructed. For space-times with SIM(2) holonomy, they describe chiral fermions propagating freely as massive particles.