Plastic Antibodies for Selective Binding of SARS-CoV-2 Spike In article number 2101925, Alex D. Batista, Beatriz Fresco-Cala, and co-workers design synthesize the very first silane-based silica core/shell molecularly imprinted polymers using an epitope peptide from spike protein as a template, which can act synthetic angiotensin-converting enzyme 2 receptor (ACE2) bind to SARS-CoV-2. The intera...

In the past few years, the sol-gel polycondensation technique has been increasingly employed with great success as an alternative approach to the preparation of molecularly imprinted materials (MIMs). The main aim of this study was to study, through a series of molecular dynamics (MD) simulations, the selectivity of an imprinted silica xerogel towards a new template-the (±)-2-(P-Isobutylphenyl)...

Submit Manuscript | http://medcraveonline.com composition and relative regular geometric structure. For example these micelles occluded in the as-synthesized mesoporous silica such as MCM-41 are the unique resource, since they are distributed in the spoke-like configuration to form numerous sub-nanometer gaps between them and the silica walls, and these inherent chemical and geometric propertie...

Mesoporous silica pillared clay (SPC) incorporated with tungstophosphoric acid (HPW) has been synthesized via in situ introducing P and W source in the acidic suspension of the clay interlayer template during the formation of the silica pillared clay. The samples were characterized by XRD, XRF, FT-IR, TG-DTA, N(2) adsorption-desorption, and SEM techniques. The results showed that the HPW formed...

Biological templates such as virions or protein assemblies have several surface functional groups that can complicate the elucidation of the fundamental mechanism(s) governing the sorption and mineralization of metals on the surface of the template. Surface functionalized silica nanoclusters with hydroxyl, amine, or thiol groups serve as surrogates for understanding the interaction between indi...

We report a preparation method for the synthesis of monodisperse magnetic polymer/silica hybrid microspheres using polymer microspheres incorporated with magnetic nanoparticles as a novel template. Monodisperse, hierarchically mesoporous, silica microspheres embedded with magnetic nanoparticles were successfully fabricated after the calcination of the hybrid microspheres. The magnetic nanoparti...

Hollow hard shell particles of 200 nm and 2 micron diameter with a 10 nm thick porous silica shell have been synthesized using polystyrene templates and a sol-gel process. The template ensures than the hollow particles are monodispersed, while the charged silica surface ensures that they remain suspended in solution for weeks. When filled with perfluorocarbon gas, the particles behave as an eff...

In this study, MCM-41 mesoporous silica nanoparticles (NPs) and MCM-41÷Fe3O4 mesoporous silica NPs were prepared by sol-gel method using CTAB (cetyltrimethylammonium bromide) as template and TEOS (tetraethyl orthosilicate) as silica precursor in order to use these materials as drug delivery system (DDS) for different biologically active agents. The MCM-41 and MCM-41÷Fe3O4 mesoporous silica NPs ...

The synthesis of hollow carbon nanospheres or capsules has attracted considerable attention because of their potential applications in catalyst supports, fuel cells, gas storage and separation, and lithium-ion batteries, which result from their unique features, such as high surface-to-volume ratio and high structural stability. Templating is the method widely used to synthesize hollow carbon sp...

Many peptides self-assemble to form amyloid fibrils. We previously explored the sequence propensity to form amyloid using variants of a designed peptide with sequence KFFEAAAKKFFE. These variant peptides form highly stable amyloid fibrils with varied lateral assembly and are ideal to template further assembly of non-proteinaceous material. Herein, we show that the fibrils formed by peptide vari...