Interactions between learners and pedagogical agents may take on a more or less social tone, dependent on many possible factors. We investigate the effects of manipulating agent dialog on learner-agent interpersonal relations, which is hypothesized to promote learning. We have implemented our model of social instructional dialog (SID) in an agent in a virtual learning environment for instructin...

251, Treatment interruption did not impact efficacy or long-term safety of dupilumab: A phase 3 open-label trial. Lisa Beck et al. International Psoriasis Council Symposium: Scientific and Clinical Advances in Psoriasis: 2017 and Beyond 12:00 pm – 1:30 pm B113-116 1:05 pm Abstract #190, Pediatric psoriasis is an independent risk factor for comorbidity development Megha Tollefson, MD Medical Der...

Like DNA replication or chromosome segregation, cytokinesis is a once-and-only-once event in the life of a cell. What controls where, when and how a cell divides? The fission yeast Schizosaccharomyces pombe has recently become a focus for genetic studies of eukaryotic cytokinesis, and this work has revealed, among other things, a novel signal transduction pathway controlling septation [1–3]. Wh...

OBJECTIVE The goal of this study was to investigate the effects of dietary standard ileal digestible (SID) valine:lysine ratios on performance, intestinal morphology, amino acids of liver and muscle, plasma indices and mRNA expression of branched-chain amino acid (BCAA) metabolism enzymes. METHODS A total of 144 crossbred pigs (Duroc×Landrace×Large White) weaned at 28±4 days of age (8.79±0.02...

It is well known that MFCC based speaker identification (SID) systems easily break down under mismatched train and test conditions. In this study, we report on evaluation of four different single-channel speech enhancement front-ends for robust SID under such conditions. Speech files from the YOHO database are corrupted with four types of noise including babble, car, factory, and white at five ...

Objective. To describe the chloride balance in infants born 25-32-week gestation, analyze the association of chloride changes with hydroelectrolytic status and their relationship with perinatal conditions, morbidities, and neurological outcome. Methods. For 7 days after birth, sodium and chloride balance, plasma potassium, phosphate, and total carbon dioxide (tCO(2)) were prospectively determin...

Distillers dried grains with solubles (DDGS) are produced by drying a mixture of wet distillers grains and condensed solubles. During this process, some of the ε-NH2 groups in Lys may be bound to reducing sugars through the Maillard reaction. This Lys is called unreactive Lys, whereas Lys that is not bound to reducing sugars is called reactive Lys. It has been suggested that the conventional pr...

A study was conducted to determine the standardized ileal digestibility (SID) of AA and calculate the NE value for regular-oligosaccharide, micronized full-fat soybean (R-MFFSB), low-oligosaccharide, micronized full-fat soybean (LO-MFFSB), lentil, and enzymatically hydrolyzed casein (EHC) for growing pigs. Six ileal-cannulated barrows (31.4 kg BW) were fed 6 diets in a 6 × 6 Latin square. Five ...

Double-stranded RNA (dsRNA) triggers RNA interference (RNAi) to silence genes of matching sequence. In some animals this experimentally induced silencing is transported between cells, and studies in the nematode Caenorhabditis elegans have shown that the dsRNA channel SID-1 is required for the import of such transported silencing signals. Gene silencing can also be triggered by endogenously exp...