Internalization and traffic to acidic endosomes of anthrax lethal factor (LF) and protective antigen (PA), bound to the anthrax toxin receptor (ATR), is required for LF translocation into the cytosol, where it can elicit its toxic effects. Dynamin is required for clathrin-mediated endocytosis, and long-term disruption of dynamin function blocks internalization of PA. We have used LFn-DTA, a sur...

OBJECTIVE This preliminary study aimed to investigate the effects of long-term frequent ketamine treatment on cognitive function in [AQ-A] CRPS patients. DESIGN A total of 30 CRPS patients were divided into two groups based on both the duration and frequency of ketamine treatment; the long-term frequent ketamine treatment (LF) group (N = 14) and the Non-LF group (N = 16). Participants were as...

We describe spine form LF, a version of LF syntactically restricted to canonical forms, and use this framework to begin a logical presentation of the term language used within Twelf, which is (among other things) an implementation of LF. This is not a self-contained document by any means, it is incomplete and furthermore assumes various levels of background in focusing systems, dependent types,...

Low-frequency repetitive transcranial magnetic stimulation of the unaffected hemisphere (UH-LF-rTMS) in patients with stroke can decrease interhemispheric inhibition from the unaffected to the affected hemisphere and improve hand dexterity and strength of the paretic hand. The objective of this proof-of-principle study was to explore, for the first time, effects of UH-LF-rTMS as add-on therapy ...

objectives: to evaluate the short-term outcome of open appendectomy, the rate of negative appendectomy as well as pathology reports after surgery in patients with suspected acute appendicitis. methods: this was a retrospective cross-sectional study being performed in nemazee hospital affiliated with shiraz university of medical science during a 2-year period between 2008 and 2010. the medical r...

in this study, combined effect of two essential oils, thymol and carvacrol, with different concentrations in two methods on gladiolous grandiflorous l. was investigated based on a completely randomized design with 3 replicates and four flower in each replicate. sansusi variety applied that was red. in short term method, different concentrations of thymol and carvacrolin including 25+25, 50+50 a...

we aimed to evaluate the potential of growing rats as a model of osteoporosis induced by short term hypercholesterolemia. twelve growing female sprague-dawley rats were randomly allocated into two groups. control rats received standard diet while rats in group 2 were fed with diet contained 20% sunflower oil, 2% cholesterol and 0.5% cholic acid for 2 weeks and then a diet contained 10% sunflowe...

abstract background: conflict is the lack of agreement and disagreement between the two men, and behavioral maladjustment or objectives that are in opposition to the other. destructive conflicts are incidents imposed on one or more than one member of the family or the whole family and affect on them. the purpose of this research is to study the effect of solution - focused short-term approach o...

BACKGROUND The definitive incorporation of heart rate variability (HRV) as a clinical tool depends on the development of more confident techniques of measurement. The length of the studies is a critical issue. Whereas Holter studies allow the monitorization at different hours and activities, short-term recordings allow the control of environmental conditions. Recording length is also strongly r...

Autonomic functioning is altered in infants born at extremely low birth weight (ELBW; <1000 g), but we know little about how such alterations manifest in adulthood. We examined associations between birth weight and resting heart rate (R-R interval), high-frequency (HF) and low-frequency (LF) heart rate variability, and systolic (SBP) and diastolic (DBP) blood pressure, in 60 participants (ages ...