Introduction: Shivering is a common side effect of central neuraxial anaesthesia. Intravenous pethidine commonly used in reducing shivering but has been associated with significant opioid effects. Dexamethasone as powerful anti-inflammatory and analgesia agent postulated to inhibit inflammatory mediators’ release thus inhibiting thermoregulatory centre, potentially attenuating post spinal shive...

Shivering is a common postoperative complication and can lead to important interferences in monitorization, addition causing discomfort the patient increased oxygen consumption. Although frequently related hypothermia, it occur normothermic patients, fact that raises importance of using pharmacological strategies for its prophylaxis treatment. The effectiveness alpha-2 agonists preventing this ...

OBJECTIVE Post anesthetic shivering is one of the most common anesthesia complications. We compared the efficacy of low-dose ketamine with normal saline in preventing post anesthetic shivering in orthopedic surgery. MATERIAL AND METHOD The present study was a prospective, randomized, double-blind, controlled clinical trial involving 183 ASA I-II patients, aged 18 to 65 years whom underwent or...

Activation of 5-HT(1A) receptors in the medullary raphé decreases sympathetic outflow to thermoregulatory mechanisms, including brown adipose tissue (BAT), thermogenesis, and peripheral vasoconstriction when these mechanisms are previously activated with leptin, prostaglandins, or cooling. These same mechanisms are also inhibited during rapid eye movement (REM) sleep. It is not known whether sh...

Core body temperature is normally tightly regulated to within a few tenths of a degree. The major thermoregulatory defences in humans are sweating, arteriovenous shunt vasoconstriction, and shivering. The core temperature triggering each response defines its activation threshold. General anaesthetics greatly impair thermoregulation, synchronously reducing the thresholds for vasoconstriction and...

Background Shivering is a frequent and undesirable complication of spinal anesthesia. It is a physiologic response to increase the body core temperature in an attempt to raise metabolic heat production. However, shivering may trigger myocardial ischemia; increase intraocular and intracranial pressures, increase wound pain, delay wound healing and interfere with pulse rate, blood pressure and el...