BACKGROUND Although non-thyroidal illness syndrome (NTIS) is considered a negative prognostic factor, the alterations in free triiodothyronine (fT3) levels in trauma patients requiring massive transfusion have not been reported. METHODS A prospective observational study comparing 2 groups of trauma patients was conducted. Group M comprised trauma patients requiring massive transfusions (>10 u...

Aim: Surgical outcomes of patients, who had Dorr type B femoral morphology, were operated on with bipolar hemiarthroplasty for hip fracture compared. Materials And Methods: This retrospective study included 352 patients at least five years follow-up. The divided into two groups: cementless (Group 1; n = 136) and cemented 2; 216). focused the following parameters: admission cost, type, gender, n...

To investigate the injury characteristics and mortality of patients transported by emergency medical services (EMS) and hospitalized for trauma following a road traffic crash, data obtained from the Trauma Registry System were retrospectively reviewed for trauma admissions between 1 January 2009 and 31 December 2013 in a Level I trauma center. Of 16,548 registered patients, 3978 and 1440 patien...

BACKGROUND Originally developed for patients with congenital factor VIII deficiency, cryoprecipitate is currently largely used for acquired hypofibrinogenemia in the context of bleeding. However, scant evidence supports this indication and cryoprecipitate is commonly used outside guidelines. In trauma, the appropriate cryoprecipitate dose and its impact on plasma fibrinogen levels are unclear. ...

BACKGROUND Early administration of tranexamic acid (TXA) has been associated with a reduction in mortality and blood product requirements in severely injured adults. It has also shown significantly reduced blood loss and transfusion requirements in major elective pediatric surgery, but no published data have examined the use of TXA in pediatric trauma. METHODS This is a retrospective review o...

Results We evaluated 2242 patients. Mean age 47.1 ± 19.02 years. Male 79%. Blunt trauma 93.9%. Injury Severity Score 22.2 ± 12.1, Revised Trauma Score 6.7 ± 1.6. Non-intentional in 84.4%, most common causes for trauma were road traffic accidents followed by pedestrian and high-energy falls. Up to 12.4% were taking antiplatelets or anticoagulants. Close to 28% had suspected or confirmed toxic in...

INTRODUCTION The massive-transfusion concept was introduced to recognize the dilutional complications resulting from large volumes of packed red blood cells (PRBCs). Definitions of massive transfusion vary and lack supporting clinical evidence. Damage-control resuscitation regimens of modern trauma care are targeted to the early correction of acute traumatic coagulopathy. The aim of this study ...

BACKGROUND Optimisation of healthcare practices in patients sustaining a traumatic brain injury is of major concern given the high incidence of death and long-term disabilities. Considering the brain's susceptibility to ischaemia, strategies to optimise oxygenation to brain are needed. While red blood cell (RBC) transfusion is one such strategy, specific RBC strategies are debated. We aimed to ...