A shiplift is a modern alternative for these older systems. It consists of a structural platform that is lifted and lowered exactly vertical, synchronously by a number of hoists. First, the platform is lowered underwater, then the ship is floated above the support, and finally the platform with ship is lifted and the ship is brought to the level of the harbor. The modern ship lifts use synchron...

AIM To explore the mechanism by which microRNA-155 (miR-155) regulates the pathogenesis of experimental colitis. METHODS A luciferase assay was performed to confirm the binding of miR-155 to the SHIP-1 3'-UTR. MiR-155 mimics, negative controls and SHIP-1 expression/knockdown vectors were established and then utilized in gain- and loss-of-function studies performed in raw264.7 cells and primar...

BACKGROUND Body mass index (BMI) and serum 25-hydroxy vitamin D3 (25OHD) concentrations are inversely related. As BMI contains only limited information regarding body fat distribution, we aimed to analyze the cross-sectional associations of abdominal visceral or subcutaneous adipose tissue, next to common adiposity measures, with the 25OHD concentration. METHODS Data were obtained from three ...

The SH2-containing inositol-5'-phosphatase, SHIP, represses the proliferation, survival, and activation of hematopoietic cells, in large part by translocating to membranes following extracellular stimulation and hydrolysing the phosphatidylinositol-3-kinase (PI3K)-generated second messenger PI-3,4,5-P3 (PIP3) to PI-3,4-P2. SHIP-/- mice have, as a result, an increased number of monocyte/macropha...

Protein kinase C(PKC) is expressed in platelets and activated downstream of protease-activated receptors (PARs) and glycoprotein VI (GPVI) receptors. We have previously shown that PKCpositively regulates PAR-mediated dense granule secretion, whereas it negatively regulates GPVI-mediated dense granule secretion. We further investigated the mechanism of such differential regulation of dense granu...

In this study, we propose a Support Vector Machine (SVM) based method for ship detection in polarimetric SAR (POLSAR). Because of similarities of ship and man-made structures on land in scattering mechanisms, land and sea are first segmented by SVM according to polarimetric features and texture features; The SVM-based Recursive Feature Elimination (RFE-SVM) approach is adopted to improve the pe...

The SH2 domain-containing inositol 5'-phosphatase (SHIP) plays a key role in preventing autoimmune phenomena by limiting antigen-mediated B cell activation. SHIP function is thought to require the dual engagement of the BCR and negative regulatory coreceptors as only the latter appear capable of recruiting SHIP from the cytosol to the plasma membrane by the virtue of phosphorylated immunorecept...

Moonpool is an opening in the floor or base of a hull ship which can be used to lower tools and vehicles into the sea in a protected area. In this paper, the effect of a rectangular cross section moonpool on the resistance force of a supply vessel was investigated both by experimental and numerical methods. For both methods a 1:37.2 scale of Caspian3 surface vessel was used. Experiments were ca...

BACKGROUND The attention placed on cruise ship infectious epidemics has helped create important preventive strategies in improving food handling, sanitation, and overall cruise ship medical care. However, the incidence of serious injury in cruise ship passengers has never been fully described. In 2006, there was an increase in the number of cruise ship passengers receiving medical care at a Lev...

This paper presents a new simulation model for long-term optimization of channel depths in which the risk of ship grounding due to wave impacts can be considered for every ship transit. This new model includes four main components: (1) an exponential probability law for a number of ship departures; (2) a parametric model of the wave-induced ship motions; (3) modeling effects of tidal variations...