Expression of a constitutively activated version of the heterotrimeric G protein alpha-subunit Galphas results in the swelling and vacuolization of a specific subset of ventral nerve cord motoneurons of Caenorhabditis elegans. A second site modifier (sgs-1) that completely suppresses this neuronal degeneration has been isolated. sgs-1 was cloned and was shown to encode an adenylyl cyclase which...

Dynamic, mRNA-containing stress granules (SGs) form in the cytoplasm of cells under environmental stresses, including viral infection. Many viruses appear to employ mechanisms to disrupt the formation of SGs on their mRNAs, suggesting that they represent a cellular defense against infection. Here, we report that early in Semliki Forest virus infection, the C-terminal domain of the viral nonstru...

This study quantifies and delineates the spatial distributions, variability and uncertainties of soil arsenic (As) in the northern part of Changhua County in central Taiwan by using kriging, sequential Gaussian simulation (SGS) and simulated annealing simulation (SAS) in geographic information systems. Thousand realizations of soil As are simulated by using SGS and SAS. The impacts of the numbe...

UNLABELLED Management of subglottic stenosis (SGS) in children is still a challenge to Otorhinolaryngologists. Balloon laryngoplasty (BLP) is an endoscopic procedure, first described in 1984 for the treatment of airway stenosis. It shows promising results and seems to be more effective than other procedures. AIM To present our experience with BLP in children with SGS. MATERIAL AND METHOD Pr...

Stress Granules (SGs) are microscopically visible, phase dense aggregates of translationally stalled messenger ribonucleoprotein (mRNP) complexes formed in response to distinct stress conditions. It is generally considered that SG formation is induced to protect cells from conditions of stress. The precise constituents of SGs and the mechanism through which SGs are dynamically regulated in resp...

We identified two regulatory elements in the upstream region of the Drosophila Sgs-3 gene which are both able to bind the ecdysone receptor (EcR/USP) and the product of the fork head gene. Interestingly, only one of the EcR/USP binding sites is able to recognize in vitro-translated EcR/USP, which provides evidence for the existence of different receptor forms having different DNA binding specif...

We present a self-consistent theory of current-voltage characteristics of d-wave/d-wave contacts at arbitrary transparency. In particular, we address the open problem of the observation of subharmonic gap structure ~SGS! in cuprate junctions. Our analysis shows that ~i! the SGS is possible in d-wave superconductors; ~ii! the existence of bound states within the gap results in an even-odd effect...

Stress granules (SGs) are cytoplasmic foci that appear in cells exposed to stress-induced translational inhibition. SGs function as a triage center, where mRNAs are sorted for storage, degradation, and translation reinitiation. The underlying mechanisms of SGs dynamics are still being characterized, although many key players have been identified. The main components of SGs are stalled 48S prein...

Abstract The study aimed at extending shelf life without compromising quality of precooked chicken breast slices by various packaging and processing technologies. were packaged in modified atmosphere (MAP, 40% CO2, 60% N2), vacuum (VAC, 93% vacuum), processed with high pressure (HPP, 600 MPa, 2 min), microwave volumetric heating (MVH, 1 kW, 3 × 15 s), soluble gas stabilization (SGS, 100% 18 h, ...