Alcoholic and chloroform extracts of E. albaT. purpurea and B. diffusa were screened for antihepatotoxic activity. The extracts were given after the liver was damaged with CCl4. Liver function was assessed based on liver to boy weight ratio, pentobarbitone sleep time, serum levels of transaminase (SGPT, SGOT), alkaline phosphatase (SALP) and bilirubin. Alcoholic extract of E. alba was found to ...

OBJECTIVE To evaluate the hepatoprotective and immunotherapeutic effects of aqueous extract of turmeric rhizome in CCl4 intoxicated Swiss albino mice. METHODS First group of mice (n=5) received CCl4 treatment at a dose of 0.5 mL/kg bw (i.p.) for 7 days. Second group was fed orally the aqueous extract of turmeric at a dose of 50 mg/kg bw for 15 days. The third group was given both the turmeric...

BACKGROUND Type 2 diabetes is an endocrine disorder that affects a large percentage of patients. High blood glucose causes fatty deposits in the liver which is likely to increase in SGOT and SGPT activities. Significant increase in SGOT/SGPT and low HDL levels is observed in patients with diabetes. Serum fructosamine concentration reflects the degree of blood glucose control in diabetic patient...

S ir, I read the article “Mildly Elevated Transaminases: Excellent diagnostic c l u e f o r A n i c t e r i c L e p t o s p i r o s i s ” with interest.1 Leptospirosis can be diagnosed only by laboratory tests as clinical features are non specific. But the laboratory tests are complex and hence definite guidelines for diagnosis of human leptospirosis is necessary. I fully agree that microscopic...

AIM The aim of this study was to evaluate the impact of therapeutic and high doses of florfenicol on kidney and liver functional indicators in goat species. MATERIALS AND METHODS Six mature, healthy goats (combine breed and sex) with average weight 25 kg were selected for this study. The therapeutic (20 mg/kg b.w.) and high doses (40 and 60 mg) of florfenicol were administered for 3 days with...

Background: Little information is available on the trend in cardiovascular risk factors and hepatic enzymes in Iranian seafarers. The present study aimed to assess the pattern of obesity, hypertension, diabetes, elevated serum glutamic oxaloacetate transaminase (SGOT), and serum glutamate pyruvate transaminase (SGPT) in Iranian seafarers during 2010 to 2014. Methods: Data on cardiovascular r...

Liver cirrhosis is the result or complication of a chronic liver condition where parenchyma damaged so that its function decreases. This study aims to profile patients with at Imelda Pekerja Indonesia General Hospital in Medan for period January 2020 - December 2021. descriptive observational study. A total 40 samples medical records diagnosis (IPI) were included this Univariate analysis form f...

Serum transaminases were determined according to the method ofKarmen, Wrobleski, and LaDue (1955) (normal values for our laboratory: SGOT and SGPT up to 15 i.u./ litre), serum salicylate levels with Trinder's reagent, fibrinogen according to the method of Clauss (1957), fibrinogen degradation products (FDP) by the immunodiffusion technique (Ouchterlony), and Factor V according to the method of ...

The hepatoprotective activity of the ethanolic extract of the rhizomes of Costus speciosus (Koenig) Sm. was studied on carbon tetrachloride treated rats. The extract registered a significant fall in the levels of serum glutamyl oxalacetic acid transaminase (SGOT), serum glutamyl pyruvate transaminase (SGPT), alkaline phosphatase (ALKP), serum bilirubin (SBLN) and liver inflammation supported by...