Abstract Background Usual interstitial pneumonia (UIP) is a fatal disease that associated with poor prognosis and survival. Several growth factors such as IGFs (insulin-like factors) IGFBPs factor binding proteins) seem to take part this pathogenesis. Pirfenidone an immunosuppressant drug thought have anti-inflammatory anti-fibrotic effects both in vitro vivo. Objective To assess IGFBP1 IGFBP2 ...

In 54 patients presenting for electroconvulsive therapy, the concentration of serum potassium was measured before and after the induced convulsion modified with a standard anaesthetic technique of methohexitone and suxamethonium. It was found that there was a statistically significant rise in serum potassium, but that the duration of convulsion had no significant effect on that rise in serum po...

abstract objective cardiac dysfunction is a major cause of death in patients with beta thalassemia. in these patients, repeated blood transfusion, ineffective erythropoiesis and increased gastrointestinal iron absorption lead to iron overload in the body and this induced heart failure. left ventricular ejection fraction was measured in major beta thalassemia (β-th) patients to detect the relati...

gestational diabetes mellitus (gdm) is one of the important problems in pregnant women. this study conducted to determine association the level of serum glucose with fetal-maternal complications of gestational diabetes with insulin therapy. this study has been conducted as an existing data study, so medical records of all pregnant women with gdm that have been treated with insulin during 2 year...

BACKGROUND The anti-CD20 monoclonal antibody rituximab is an important therapeutic in Waldenstrom's macroglobulinemia (WM), producing response rates of 50-70%. Responses, which are based on serum IgM levels, have typically been evaluated at 12 weeks. Paradoxically, we have observed that serum IgM levels can abruptly rise following rituximab therapy in patients with WM, and can often lead to mor...

due to a narrow therapeutic range, measurment of theophylline serum levels is highly recommended in patients with a long-term theophylline therapy. in this regard, since blood sampling is an invasive method, exploring alternative methods using other biological fluids in particular saliva samples are targeted. this study was designed to determine any relationship between serum and saliva levels ...

Abstract Objective Thalassemia major is a severe transfusion-dependent anemia that needs iron chalation therapy to remove iron overload. The objectives of the present study were to assess the iron overload liver response to inulin of chicory supplementation by evaluating the serum ferritin and liver enzymes. Methods Among 70 beta thalassemia patients, 50 were selected for chelating therapy ...

AIM To assess serum Hepatocyte Growth Factor (HGF) levels in individuals with anxiety and to test the hypothesis that there is a relationship between HGF levels and zinc therapy. SUBJECTS AND METHODS Serum from 19 individuals with anxiety and 19 controls were tested for serum HGF using ELISAs. HGF serum concentration in individuals with anxiety before zinc and anti-oxidant therapy was compare...

this preliminary study was designed to evaluate the effects of heberon alfa for the treatment of chronic hepatitis b infected subjects in iran. a single center, open label, single treatment prospective study of interferon alfa (heberon alfa), 5 million units every other day for a period of 4 months, was performed between 1996 to 1998. a total number of 30 patients with histologically documented...