The adipocyte hormone leptin is thought to serve as a signal to the central nervous system reflecting the status of fat stores. Serum leptin levels and adipocyte leptin messenger RNA levels are clearly increased in obesity. Nevertheless, the factors regulating leptin production are not fully understood. The aim of this study was to determine the effects of in vivo administration of the syntheti...

the aim of this study was to investigate the effect of 12 weeks moderate intensity aerobic exercise on leptin and c-reactive protein serum levels in obese men. the study was conducted in urmia- iran in 2015. twenty-four obese men with an aged range 40-50 yrs. were enrolled into the study. subjects were randomized to one of 2 groups exercise (n=12) and control groups (n=12). the exercise group p...

background: polycystic ovary syndrome (pcos) is the most common endocrinopathy in women. it may involve an impairment in physiologic regulation of leptin and ghrelin. there is limited, controversial data on the relation of dietary components with leptin and ghrelin in pcos, so the current study has been conducted to explore the effects of different macronutrients on serum levels of leptin and g...

Leptin has been measured in the fetal circulation and plasma leptin may also originate from a range of other fetal and placental tissues. The present study was designed to analyze leptin levels in women with preeclampsia and to assess its relationship with renal functions, gestational age and outcome of pregnancy. Twenty five normotensive pregnant women and 25 age and gestation matched preeclam...

PURPOSE The effects of gonadotropin-releasing hormone agonist (GnRHa) treatment on the energy metabolism in girls with central precocious puberty (CPP) are controversial. We focused the changes and related factors of serum levels of leptin and adiponectin in girls with CPP before and during GnRHa treatment. METHODS Thirty girls with idiopathic CPP were enrolled in the study. Their auxological...

Received:October 3, 2005 Accepted:December 20, 2005 ABSTRACT Objective: To elucidate whether and how in patients with uremia on hemodialysis the level of CRP as the marker of inflammation correlate with serum leptin. Patients and Methods: Serum leptin and CRP were determined on patients with ESRD on hemodialysis Results: The total patients were 36 (f =15, m=21). The mean patient's age were 46 (...

Background: To determine the relationship between serum leptin and insulin resistance in obese Pakistani subjects. Methods: In this observational study fifty healthy obese and overweight subjects were selected by nonprobability convenience sampling. Age, sex, height, weight and body mass index (BMI) of subjects were recorded. Fasting plasma glucose, serum leptin and insulin were measured. Fifty...

The Ob protein leptin has been shown to be closely correlated with measures of body fat in humans and animals. Studies have suggested that there are both gender and ethnic differences in serum leptin concentrations, even after controlling for total and relative body fat and body mass index. We hypothesized that gender and ethnic differences in serum leptin concentrations are due to differences ...