PURPOSE Serum alkaline phosphatase (ALP) level is the most valid marker of bone formation. Precocious puberty (PP) in girls is characterized by early growth acceleration. The aim of this study was to determine whether serum ALP levels differ between girls with PP and those with normal puberty, and whether ALP level varies with age or Tanner stage. METHODS This retrospective study included gir...

A useful laboratory test for the differentiation of liver, bone, and intestinal alkaline phosphatase (ALP) isoenzymes in serum is presented. Electrophoresis in polyacrylamide gel is performed with untreated serum as well as with serum incubated at 56 degrees C for 10 min. The heating step denatures bone isoenzyme which may obscure the liver ALP band when present in large amounts. Visualization ...

HPP is a clinically heterogeneous disease and classified into at least six forms according to severity and age of onset: perinatal (lethal), perinatal (benign), infantile (MIM [Mendelian Inheritance in Man] # 241500), childhood (MIM# 241510), adult (MIM# 146300), and odontohypophosphatasia (Mornet, 2008) (Table 1). All forms of HPP display reduced activity of unfractionated serum ALP and the pr...

The present study was designed and conducted to fi nd the appropriate physical baseline values for hepatobiliary enzymes such as, alanine aminotransferases (ALT), aspartate aminotransferases (AST), alkaline phosphatase (ALP) and gamma glutamyltransferases (GGT) in adult healthy Murrah buffaloes in hot humid climatic conditions and also to assess the ideal storage condition for buffalo sera samp...

Objective: Alkaline phosphatase (ALP) is considered a biomarker of high bone turnover in hemodialysis (HD) patients with secondary hyperparathyroidism. This study was conducted to determine whether high serum ALP levels are associated with increased all-cause mortality of HD patients. Patients and Methods: This was a retrospective cohort study conducted at a single center. The subjects were 195...

BACKGROUND The prognostic value of serum alkaline phosphatase (S-ALP) has not been fully validated for nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS S-ALP levels were measured in 601 patients newly diagnosed with NPC before radical treatment, and possible associations of these levels with 5-year overall survival (OS) and tumor-free survival (TFS) were explored using univariate and mul...

The normal serum concentration of alkaline phosphatase (ALP) in adults ranges from 47 to 147 IU/l. Alkaline is known be produced by syncytiotrophoblasts the placenta during pregnancy. Its levels are normally increased pregnant women and up twice upper limit can considered normal. There have been case reports pointing out that an abnormal rise ALP could a marker for placental insufficiency prete...

Effect of polyherbal formulation Ambrex was evaluated in butylated hydroxytoluene (BHT) induced toxicity of lungs and liver in rats. Toxicity was produced by administering BHT (500 mg/kg/day) for 3 days. Lung damage was evidenced by elevated levels of broncho alveolar lavage fluid (BAL) parameters such as protein, lactate, lactate dehydrogenase (LDH), alkaline phosphatase (ALP), acid phosphatas...

Ethanol extract of pawpaw seed was evaluated for a possible application in the management diabetes. Alloxan used to induce diabetes rats, which were subsequently study antihyperglycaemic effect extract. Four (4) treatment groups and two (2) control 8 rats each created using complete randomized design. Triglyceride (TG), total cholesterol (TC), high density lipoprotein (HDL), low-density (LDL), ...

The influence of anaemia on alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) activities in dogs infected with B. canis was investigated. Samples of blood and serum from 230 infected dogs were divided into two groups: A (with anaemia) and B (without anaemia). The differences in the activities of the enzymes between both groups were not statisticall...