Febrile urinary tract infection is the most common serious bacterial infection in childhood, but the most appropriate evaluation of children with this condition is still unclear, overall regarding the best long-term management of children after a first UTI. Here we review current recommendations for the diagnosis, treatment, imaging evaluation and use of antibiotic prophylaxis in children with ...

Most children will have been evaluated for a febrile illness by 36 months of age. Although the majority will have a self-limited viral illness, studies done before the use of Haemophilus influenzae type b and Streptococcus pneumoniae vaccines showed that approximately 10 percent of children younger than 36 months without evident sources of fever had occult bacteremia and serious bacterial infec...

Meropenem was compared with imipenem/cilastatin for the treatment of serious bacterial infections in a randomized, prospective multicentre study. Both study drugs were given intravenously 1 g every 8 h and no other antimicrobial agents were permitted concomitantly. Of the 204 patients enrolled, the treatment of 177 was evaluable for clinical efficacy and 115 for bacteriological efficacy. In the...

chlamydia trachomatis is the most prevalent sexually transmitted bacterial infection, with an estimated annual worldwide incidence of 50 million cases. a large proportion of those infected, particularly women, are asymptomatic, and these individuals serve as a major reservoir of infection. women are also at risk for serious reproductive tract complications with significant morbidity. in an effo...

background and purpose: chronic granulomatous disease (cgd) is an inherited disorder of the nicotinamide adenine dinucleotide phosphate (nadph) oxidase complex. this disorder results in recurrent life-threatening bacterial and fungal infections. aspergillus species are the most common fungal infections in these patients. case report: herein, we present a case of fungal infection in a girl with ...

OBJECTIVE Rheumatoid arthritis (RA) is a chronic inflammatory disease accompanied by many complications, and serious infections are associated with many of the advanced therapeutics used to treat it. We assessed serum procalcitonin (PCT) levels to distinguish bacterial infection from other complications in patients with RA. METHODS One hundred eighteen patients experiencing an RA flare, nonin...

Good syndrome, characterized by hypogammaglobulinemia and acquired immunodeficiency, is a rare condition associated with thymoma. A 67-year-old woman, who 4 months previously had a thymoma resected, presented with generalized hypogammaglobulinemia with a severely decreased B cell population as demonstrated by flow cytometry. She was diagnosed as having bacterial mediastinitis associated with Go...

Hospital-acquired infection is one of the major risks to patients and an economic burden on healthcare system, multidrug resistance a serious complicating factor in providing effective treatment. Novel drug delivery systems for antimicrobial agents can act as solution infection. In this study we demonstrate biomaterial with properties through incorporation ciprofloxacin into p(HEMA: MMA) polyme...