Phosphataemia has been investigated in 54 patients with Gram-negative septicaemias; either absolute (serum phosphate <2 mg./100 ml.) or relative (P./B.U.N. 0.04) hypophosphataemia was found in 69% of all determinations. In 37 patients with Gram-positive septicaemias hypophosphataemia was present in only 24%, many of whom had additional Gram-negative bacteriuria and possible Gram-negative septic...

Finding two or more genotypes of a single species within an infected sample is a not infrequent event. In this work, three Escherichia coli strains of decreasing extra-intestinal virulence (pathogenic B2S and B1S strains, and the avirulent K-12 MG1655 strain) were tested in septicaemia and urinary tract infection (UTI) mouse models, either separately or in pairs. Survival was monitored and bact...

INTRODUCTION the deadly threat of systemic infections with coagulase negative Staphylococcus lugdunensis despite an appropriate antibiotic therapy has only recently been recognized. The predominant infectious focus observed so far is left-sided native heart valve endocarditis, but bone and soft tissue infections, septicaemia and vascular catheter-related bloodstream infections have also been re...

Possession of P fimbriae, virulence-associated O and K antigens, haemolysin and aerobactin production, and susceptibility to 10 antimicrobial agents were studied in 63 Escherichia coli strains isolated from blood or CSF of infants who were grouped according to their clinical characteristics. These isolates were compared with 35 faecal E. coli strains from healthy infants. Individual virulence f...

The incidence of neonatal septicaemia caused by group B streptococci in our hospital during 1980-6 was 9 1/10 000 births, which is three times higher than the average rate in the United Kingdom.2 Despite this, mortality during this period was only 5% (one death in 20 cases), which is one seventh the national average of 36%1; we ascribe this to the early antibiotic treatment of neonates with tac...

I can recall a suggestion which I made at a meeting of the Surat Medical Union in 1920, in a discussion on the treatment of plague. One can only understand the pathology of plague when one comes to examine cases at post-mortem examination. The majority of cases die before the sixth day of illness and show profound pathological changes in the heart and other organs. The condition present is a se...

In recent years, it has become increasingly popular for pet owners to feed their dogs and cats raw meat as an alternative processed, manufactured diets. Owners are often unaware of the potential risks this may pose animals themselves, despite published literature. This article reports case a 5-month-old female French Bulldog referred investigation acute vomiting, diarrhoea pyrexia. She was diag...

A prospective study of 486 high risk neonates admitted to a level II nursery in a relatively poor and rural area of Malaysia was carried out to determine the incidence, the spectrum of micro-organisms and predisposing factors in relation to early onset septicaemia. The incidence of proven or probable septicaemia was 57.61 per 1000 high risk newborns over 1.5 kg. The case fatality was 10.71 per ...

BACKGROUND Neonatal septicaemia remains a major cause of morbidity and mortality. The aetiology, risk factors and outcome of this problem need to understood. OBJECTIVE To determine the aetiology, risk factors and immediate outcome of bacteriologically confirmed neonatal septicaemia in Mulago hospital. METHODS Blood cultures were aseptically obtained from neonates presenting with clinical se...