OBJECTIVE The effects of natural adjuvants on lung inflammation and tracheal responsiveness were examined in sensitized guinea pigs. METHODS The responses of guinea pig tracheal chains and the serum levels of interleukin-4 and interferon-gamma were examined in control pigs and three other groups of guinea pigs: the sensitized group and two other sensitized groups treated with either adjuvant ...

BACKGROUND Patients sensitized to common pets (cat, dog) frequently display an immunoglobulin (Ig) E-mediated response to allergens from other animals. OBJECTIVE To evaluate whether individuals sensitized to common pets might be at higher risk of developing allergic sensitization to other mammalian allergens. METHODS The study population comprised 900 consecutive patients (300 individuals s...

The immunochemical specificity of antigen-induced inhibition of peritoneal exudate cell migration was studied in animals sensitized to chemically defined alpha,DNP(Lys)(18) peptides. It was shown that sensitized peritoneal exudate cells could discriminate between various DNP-oligolysines. Only immunogenic members of the homologous series of alpha,DNP-L-lysines equal to or larger in size than th...

No data on the relationship between allergic sensitization to animal dander and milk allergens are available in literature in adults. Considering the high rate of allergic sensitization to mammals in atopic adults living in Naples area, we aimed to evaluate if sensitization to milk allergens could be a risk factor for these subjects. From 755 consecutive outpatients examined between May 1 2009 ...

Mitchell, Paul D. (West Virginia University Medical Center, Morgantown), and John M. Slack. Hyper-reactivity of rabbits sensitized with Bartonella bacilliformis. J. Bacteriol. 92:769-779. 1966.-Sensitization with viable cells of Bartonella bacilliformis increased the susceptibility of rabbits to the lethality of subsequently administered Bartonella metabolites. In animals sensitized with 3 week...

BACKGROUND A limitation with current imaging strategies of recurrent glioma undergoing radiotherapy is that tumor and radiation injury cannot be differentiated with post contrast CT or MRI, or with PET or other more complex parametric analyses of MRI data. We propose to address the imaging limitation building on emerging evidence indicating that effective therapy for recurrent glioma can be att...

In connection with several recent publications"' on reaction in children after injection of H. pertussis vaccine, it might be of interest to report our own observations on the action of antihistaminic drugs on mice sensitized by this vaccine. In a previous publication8 it was reported that treatment of mice with H. pertussis vaccine renders these animals highly sensitive to histamine. These fin...

objective(s):with regard to pharmacological effects of carvacrol on the respiratory system, its effect on cytokines genes expression in splenocytes of asthmatic mice was examined in this study. materials and methods:splenocytes were isolated from non-sensitized (control group), sensitized mice to ovalbumin (ova) (group s), and s animals treated with dexamethasone, and three concentrations of ca...

Performance of instrumental actions in rats is initially sensitive to postconditioning changes in reward value, but after more extended training, behavior comes to be controlled by stimulus-response (S-R) habits that are no longer goal directed. To examine whether sensitization of dopaminergic systems leads to a more rapid transition from action-outcome processes to S-R habits, we examined perf...

Repeated administration of morphine sensitizes animals to the stimulant and rewarding properties of the drug. It may also alter the expression and function of GABA receptors within the ventral tegmental area (VTA), a midbrain region that is implicated in morphine action. In the present study, the effect of activation of GABAB receptor subtypes within the VTA on morphine-induced incentive sensit...