This study was designed to investigate the anti-diabetic effects of selenium nanoparticles (SeNPs) at dose 2 mg/kg body weight in streptozotocin (STZ) induced diabetes rats 50 weight. Were administered orally normal and experimentally diabetic for 35 days glibenclamide (Glib) rate 20 used as a reference drug. 48 waster male divided into 6 equal groups each 8 rats. Blood samples pancreatic tissu...

Abstract In the present era, due to increasing incidence of environmental stresses worldwide, developmental growth and production agriculture crops may be restrained. Selenium nanoparticles (SeNPs) have precedence over other because significant role selenium in activating defense system plants. addition beneficial microorganisms, use biogenic SeNPs is known as an environmentally friendly ecolog...

This investigation aimed to characterize the green synthesized selenium nanoparticles using Sonchus maritimus L. extract and evaluate their antioxidant antibacterial properties. Moreover, acute toxicity of was performed in Wistar rats. The synthesis SeNPs confirmed by Ultraviolet-visible, Fourier Transform Infrared Spectroscopy, Scanning Electron Microscopy Energy Dispersive X-ray analysis. Ant...

Most cancer cells exhibit a shift in glucose metabolic strategy, displaying increased glycolysis even with adequate oxygen supply. SUMO-specific proteases (SENPs) de-SUMOylate substrates including HIF1α and p53,two key regulators in cancer glucose metabolism, to regulate their activity, stability and subcellular localization. However, the role of SENPs in tumor glucose metabolism remains unclea...

Small ubiquitin-related modifier (SUMO) is involved in numerous cellular processes including protein localization, transcription, and cell cycle control. SUMOylation is a dynamic process, catalyzed by three SUMO-specific enzymes and reversed by Sentrin/SUMO-specific proteases (SENPs). Here we report the characterization of these proteases in Schistosoma mansoni. Using in silico analysis, we ide...

In an effort to prevent the formation of pathogenic biofilms on hydroxyapatite (HA)-based clinical devices and surfaces, we present a study evaluating the antimicrobial efficacy of Spherical biogenic Se-Nanostructures Embedded in Organic material (Bio Se-NEMO-S) produced by Bacillus mycoides SelTE01 in comparison with two different chemical selenium nanoparticle (SeNP) classes. These nanomateri...

Abstract NK cells-based cancer therapy combined with chemotherapeutic drugs for the treatment of tumors can enhance immunosensitivity cells, increase expression cell receptors, and eventually boost killing effect cells on cells. Selenium (Se) different chemical structures be metabolized into selenoproteins to regulate tumor immune cells’ fate functions. Herein, we found that, functionalized Se ...

In this study, we developed a method to prepare inorganic nanoparticles in situ on the surface of cationized cellulose using rapid microwave-assisted synthesis. Selenium (SeNPs) were employed as novel type antimicrobial agent and, same method, silver (AgNPs) also prepared. The results demonstrated that both SeNPs and AgNPs about 100 nm size generated fabrics. antibacterial tests revealed presen...