INTRODUCTION P wave axis is one of the most practical clinical tool for evaluation of cardiovascular disease. The aim of our study was to evaluate the P wave axis in electrocardiogram (ECG), left atrial function and association between the disease activity score in patients with systemic lupus erythematosus (SLE). METHODS Standard 12-lead surface ECGs were recorded by at a paper speed of 25 m...

OBSErve Germany was the first observational study of belimumab as add-on treatment for systemic lupus erythematosus (SLE) in routine clinical care in Germany, retrospectively collecting data from 102 SLE patients, 6 months before and after belimumab initiation. Most patients had moderate or severe SLE and several SLE manifestations. After 6 months of belimumab treatment, 78% of patients showed ...

Lupus nephritis is one of the most severe Systemic Lupus Erythematosus features, defining treatment modality and prognosis. Our retrospective study, including 178 patients treated for lupus nephritis during 23 years with mostly cyclophosphamide-based initial regimens followed by azathioprine or mycophenolic acid, demonstrates 84.8% of renal response with 19.2% of flares, 15-year patient surviva...

Reconsiderations of home have been crucially examined in Caribbean cultural productions. As Jamil Khader argues in her article on “Subaltern Cosmopolitanism: Community and Transnational Mobility in Caribbean Postcolonial Feminist Writings,” Caribbean feminists are faced with the task of challenging a conventional idea of home that has historically located women and other marginal subjects under...

Background/Purpose Serositis is one of both ACR and SLICC classification criteria for systemic lupus erythematosus (SLE) and a common type of extra renal flare. However, little is known about clinical or immunological associations of pleurisy or pericarditis. The aim of this study is to analyze associates and predictors of pleurisy versus pericarditis in Caucasians and African Americans with SL...

Serotonin neurons originate from the brainstem raphe nuclei and innervate the entire brain to regulate mood, emotion, sleep, appetite and aggression. Previous electron microscopy (EM) studies have revealed that 5-HT boutons directly contact several neuronal populations via asymmetrical (excitatory) or symmetrical (inhibitory) synapses. Additionally, 5-HT boutons sometimes form “triads” with the...

The work characterizes develop a single layer bioinorganic membrane using nano-molecule Kurumi C13H20BeLi2SeSi / C13H19BeLi2SeSi, is well characterize computationally. As its scientific name 3-lithio-3-(6-{3-selena-8-beryllatricyclo [3.2.1.02,⁴] oct-6-en-2-yl}hexyl)-1-sila-2-lithacyclopropane. was based on molecular dynamics (MD) of 1ns, the CHARMM22 force field, with step 0.001 ps. Calculation...

Located within the Phong Nha-Ke Bang National Park, Central Vietnam, Son Doong Cave is world’s largest cave and has become one of most famous sites for caving tourists scientists worldwide. It contains highly diverse landscapes ecosystems with special value in many natural aspects including biodiversity. Bat species are usually regarded as key fascinating dwellers ecosystems. We recently conduc...

This paper provides a comparison between Earthquake Loss Estimation (ELE) software packages and their application using an “Open Source Procedure for Assessment of Loss using Global Earthquake Modelling software” (OPAL). The OPAL procedure was created to provide a framework for optimisation of a Global Earthquake Modelling process through: 1. overview of current and new components of earthquake...

OBJECTIVE To describe the objectives, design and methods of the Spanish Society of Rheumatology systemic lupus erythematosus (SLE) registry (RELESSER). METHODS Multicenter, hospital-based registry, with retrospective collection of data from a large representative sample of adult patients with SLE (1997 ACR criteria) attending Spanish rheumatology services. The registry includes demographic da...