Neurons in the supplementary eye field (SEF) of the macaque monkey exhibit rank selectivity, firing differentially as a function of the phase attained during the performance of a task requiring the execution of saccades to a series of objects in fixed order. The activity of these neurons is commonly thought to represent ordinal position in the service of serial-order performance. However, there...

Anticipatory movements are motor responses occurring before likely sensory events in contrast to reflexive actions. Anticipatory movements are necessary to compensate for delays present in sensory and motor systems. Smooth pursuit eye movements are often used as a paradigmatic example for the study of anticipation. However, the neural control of anticipatory pursuit is unknown. A previous study...

Surface enhanced fluorescence (SEF) utilizes the local electromagnetic environment to enhance fluorescence from the analyte on the surface of a solid substrate with nanostructures. While the detection sensitivity of SEF is improved with the development of nano-techniques, detection of multiple analytes by SEF is still a challenge due to the compromise between the high enhancing efficiency and b...

A SEF (software exchange format), such as GXL [6], TA [4] or RSF [7], is used to exchange data between tools that analyze software. Researchers at Bell Canada have specified the Datrix [3] SEF in TA (and soon to be, GXL) for C, C++ and Java. It is designed so that a parser for the language, C, C++ or Java, can read a source program and emit the program’s Abstract Syntax Tree (AST) in the Datrix...

We report the cloning and expression analysis of a mouse gene encoding a novel transmembrane protein. Expression of Sef is similar to that of Fgf8 and Spry2 during early embryogenesis, being prominent in the forebrain, mid-hindbrain boundary, branchial arches, somites, limb bud and tailbud of mouse embryos. These expression profiles indicate that Fgf8, Spry2 and Sef belong to a synexpression gr...

The concept of the “linear model of innovation” (LMI) was introduced by authors belonging to the field of innovation studies in the middle of the 1980s. According to the model, there is a simple sequence of steps going from basic science to innovations – an innovation being defined as an invention that is profitable. In innovation studies, the LMI is held to be assumed in Science the endless fr...

Six patients underwent cardiac catheterization before and after occurrence of a myocardial infarction. Results from the two procedures allowed the quantitation of changes in coronary artery anatomy and left ventricular performance associated with myocardial infarction. Left ventricular biplane or single plane angiography and selective coronary angiography were used to evaluate coronary artery a...

Selenocysteine is the 21st naturally-occurring amino acid. Selenoproteins have diverse functions and many remain uncharacterized, but they are typically associated with antioxidant activity. The incorporation of selenocysteine into the nascent polypeptide chain recodes the TGA stop codon and this process depends upon a number of essential factors including the selenocysteine elongation factor (...

Six patients underwent cardiac catheterization before and after occurrence of a myocardial infarction. Results from the two procedures allowed the quantitation of changes in coronary artery anatomy and left ventricular performance associated with myocardial infarction. Left ventricular biplane or single plane angiography and selective coronary angiography were used to evaluate coronary artery a...

WUSCHEL (WUS) is essential for preventing stem cell differentiation in Arabidopsis. Here we report that in addition to its functions in meristematic stem cell maintenance, WUS is involved in the regulation of cell division. The WUS gain-of-function mutant, stem ectopic flowers (sef), displayed elongated hypocotyls, whereas the loss-of-function wus-1 mutant had shortened hypocotyls. The long hyp...