The study evaluated the in vitro iron chelating, lipid peroxidation inhibitory and DNA protective activities of hydroalcoholic (60% ethanolic) extracts of various plant parts of Terminalia chebula, Caesalpinia crista, Cajanus cajan, Terminalia belerica, Emblica officinalis, and Tinospora cordifolia. The iron chelating property of the plants is in accordance with the order of their IC50 values f...

The genus Tinospora includes 34 species, in which several herbs were used as traditional medicines by indigenous groups throughout the tropical and subtropical parts of Asia, Africa, and Australia. The extensive literature survey revealed Tinospora species to be a group of important medicinal plants used for the ethnomedical treatment of colds, headaches, pharyngitis, fever, diarrhea, oral ulce...

The role of aqueous extract of Tinospora cordifolia [TC], in preventing methotrexate [MTX] induced oxidative damage in rat liver was studied. Sixty Wistar albino rats were divided into five groups with twelve rats in each group. Group I served as normal control group. To group II rats, MTX was administered at 5mg/kg body weight intraperitoneally for three consecutive days. Rats in group III wer...

The inevitable development of chemoresistance and unmanageable side effects are the major therapeutic challenges in management of breast cancer imposing an urgent need for identification of novel therapeutic agents. In the present investigation, we report anti-proliferative activity of chloroform fraction of Tinospora cordifolia (TcCF), an Ayurvedic medicinal plant, on breast cancer cells. We f...

Ayurveda is one of the oldest systems medicine in world. There are almost 1200 plants mentioned for their medicinal properties. Thus, Pharma therapeutics mainly centered on use various plant parts management innumerable diseases. Guduchi (Tinospora cordifolia (Willd.) Hook. F. & Thoms.) Is such praise widely its efficacy treatment diseases along with superior rejuvenation property? Ayurvedic ph...

BACKGROUND Makaradhwaja a gold containing mercurial preparation used for diabetes mellitus in indigenous system of medicine. It is a popular aphrodisiac and rejuvenator traditional medicine. It is prepared by using processed gold, mercury and sulfur in different ratios by applying intermittent heating pattern in Valuka Yantra. OBJECTIVES The aim of the study was to evaluate anti-diabetic effe...