Black cumin seed oil (MBJH) ( Nigella sativa L .) is a well-known herb with pharmacology activities such as anticancer and anti-thrombocytopenia. The limitation of MBJH has poor absorption when using oral dosage form. liquid SNEDDS (Self-nanoemulsifying drug delivery system) an alternative formulation. However, the disadvantage liquid-SNEDDS MJBH was interaction between active ingredients soft ...

BACKGROUND Self-emulsifying drug delivery system is an isotropic mixture of natural or synthetic oils, non-ionic surfactants or, one or more hydrophilic solvent and co-solvents/surfactant and polymer that improve bioavailability and increase solubility of poorly-soluble drugs. OBJECTIVES This study was aimed to prepare and develop a stable formulation for self-emulsifying drug delivery system...

Abstract Background Self-emulsifying drug delivery systems (SEDDSs) have attracted attention because of their effects on solubility and bioavailability lipophilic compounds. Herein, a SEDDS loaded with lycopene purified from red guava (nanoLPG) was produced. The nanoemulsion characterized using dynamic light scattering (DLS), zeta potential measurement, nanoparticle tracking analysis (NTA), tra...

The aim of the current study was the development of a new pellet based self-emulsifying (SE) drug delivery system for the oral delivery of poorly soluble drugs. Furthermore, we wanted to investigate the influence of physiological dilution media and enzymatic digestion on the solubilization capacity of the formulation for the model drug Progesterone. Lipid mixtures composed of Solutol HS 15 and ...