نتایج جستجو برای: secondary hematologic malignancy
تعداد نتایج: 360152 فیلتر نتایج به سال:
During the last decades, several improvements in treating gynecological malignancies have been achieved. In particular, target therapies, mostly monoclonal antibodies, have emerged as an attractive option for the treatment of these malignancies. In fact, various molecular-targeted agents have been developed for a variety of malignancies with the objective to interfere with a precise tumor assoc...
Abnormalities of hemoglobin synthesis are usually inherited, but may also arise as a secondary manifestation of another disease, most commonly hematologic neoplasia. Acquired hemoglobin disorders can be seen in any population and are not restricted to areas of the world with a high incidence of inherited hemoglobinopathies. In fact, the acquired hemoglobinopathies may be more readily recognized...
Round cell tumors of the skin in the adult constitute one of the diagnostic challenges for histopathologists, because their differential diagnosis covers a broad spectrum of tumors of epithelial as well as non-epithelial origins. As the first step towards the correct diagnosis, immunohistochemical screening of the tumor sample by CD45 (leukocyte common antigen, LCA) antibody is thought to be us...
A lack of DNA mismatch repair on an athymic murine background predisposes to hematologic malignancy.
Inheritance of a germline mutation in one of the DNA mismatch repair genes predisposes human individuals to hereditary nonpolyposis colorectal cancer, characterized by development of tumors predominantly in the colon, endometrium, and gastrointestinal tract. Mice heterozygous for a mismatch repair-null mutation generally do not have an increased risk of neoplasia. However, mice constitutively l...
The United States Centers for Disease Control and Prevention reported over 1000 cases of severe respiratory disease in pediatric patients associated with enterovirus D68 (EV-D68) in the fall of 2014. We sought to identify and define the clinical burden of disease due to EV-D68 in adult patients with hematologic malignancy or undergoing hematopoietic cell transplant (HCT). Real-time reverse-tran...
Allogeneic stem cell transplantation is curative for certain cancers, but the high doses of chemotherapy/radiotherapy lead to toxicity. Here, we treat patients with refractory cancer with 100 cGy total body irradiation (TBI) followed by infusion of nonmobilized pheresed allogeneic peripheral blood cells. Twenty-five patients, with a median age of 47 years, with refractory cancers were enrolled....
BACKGROUND Synovial sarcomas are uncommon malignancies that mainly affect adolescents and young adults. Most arise from the deep soft tissues of the extremities, but they can occur in other parts of the body such as the lung. Synovial sarcomas after radiation therapy are rare, in contrast with other sarcomas, with only six reported cases. Secondary malignancies after radioactive iodine (RAI) th...
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