Collision tumors or metastasis from an extracranial tumor to a primary brain neoplasm are rare but do occur. The majority involve metastases to meningiomas. This case presents the second documented collision of a systemic chronic lymphocytic leukemia (CLL) to a glioblastoma multiforme (GBM). Lymphomas tend to coalesce in perivascular locations, and the characteristic vascularity of glioblastoma...

neurofibromatosis type 2 is an inherited disease. the main manifestation of the disease is the development of symmetric, non-malignant brain tumors in the region of the cranial nerve viii usually as schwannoma. we report here a 20-year-old woman with primary intracranial malignant nerve sheath tumor located in the left cerebellopontine angle. histologically, the tumor showed malignant spindle c...

Owing to recent advances in diagnostic and surgical techniques for cancer, a patient diagnosed with two or more neoplasms is not rare. We report on the case of a 58-year-old male with multiple primary malignant neoplasms, who suffered from three histological types of malignant neoplasm in six organs, namely the glottis, renal pelvis, urinary bladder, oral floor, prostate, and esophagus in chron...

Chondrosarcoma, the second most common primary malignancy of the bone, is malignant cartilage forming tumour that very rarely involves the axial skeleton. It may arise as a primary bone tumour or as a secondary lesion from a preexisting benign cartilaginous neoplasm such as osteochondroma or enchondroma. A rare case of a massive secondary lumbar spine chondrosarcoma is presented. Management con...

A variety of Tand B-cell neoplasm can involve the skin and the term “primary cutaneous lymphoma” refers to the disorder that present in the skin with no evidence of extracutaneous disease at the time of diagnosis [1,2]. Among them, primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL, LT) is characterized with skin lesions on one or both legs. In patients presenting with a single ...

BACKGROUND We aimed to identify patterns and predictors of second primary malignancy (SPM) of the aerodigestive tract (SPMADT) in patients with squamous cell carcinoma of the oral cavity (SCCOC) and larynx (SCCL). METHODS One thousand two hundred fifty-seven patients from two existing databases were studied: 595 with SCCOC (1986-1995) and 662 with SCCL (1984-1998). The primary endpoint of int...

The performance of combining fecal immunochemical tests (FITs) and a high-risk factor questionnaire (HRFQ) in colorectal cancer (CRC) screening in economically and medically underserved populations is uncertain. This study investigated the performance of a CRC screening protocol of combining FITs and an HRFQ as primary screening methods in a rural Chinese population. A CRC mass screening was co...

Non-Hodgkin's lymphoma of B-cell type is the second most common neoplasm after Kaposi's sarcoma, among patients with human immunodeficiency virus infection. Most non-Hodgkin's lymphoma cases that are associated with acquired immunodeficiency syndrome involve extranodal sites, especially the digestive tract and the central nervous system. We report a case of primary lymphoma of the duodenum in a...