INTRODUCTION Acne vulgaris is a common chronic inflammatory disease of the pilosebaceous unit triggered by Propionibacterium acnes. A bakuchiol, Ginkgo biloba extract, and mannitol (BGM) complex has been developed to provide patients with acne with a specific dermocosmetic to be used adjunctively with conventional treatments. OBJECTIVE The aim of these studies was to assess the antibacterial,...

Occupants of former methamphetamine laboratories, often residences, may experience increased exposure through the accumulation of the methamphetamine in the organic films that coat skin and indoor surfaces. The objectives of this study were to determine equilibrium partition coefficients of vapor-phase methamphetamine with artificial sebum (AS-1), artificial sebum without fatty acids (AS-2), an...

In this study, we assessed the efficacy and safety of four skin care products indicated for skin hydration (Aqua Therapy and Perfecta), skin aging (Unica Resurfacing Therapy) and sensitive skin (Comfort Therapy), in four groups of 7 volunteers with different skin types. These products belong to four skin care ranges (Aqua, Perfecta, Unica and Comfort) and are formulated with a specific combinat...

Skin surface lipid (SSL) film is a mixture of sebum and keratinocyte membrane lipids, protecting skin from environment. Its composition is unique for the high percentage of long chain fatty acids, and of the polyterpenoid squalene, absent in other human tissues, and in non-human Primates sebum. Here, the still incomplete body of information on SSL as mediators of external chemical, physical, an...

BACKGROUND.: Post-adolescent acne is an inflammatory disorder, whose cause is unknown. Contrasting data are available on correlation between acne and smoking habit. OBJECTIVES.: To verify the frequency of clinically non-inflammatory (atypical) post-adolescent acne (APAA) among women, a possible correlation with cigarette smoking, possible differences in sebum composition in a group of female sm...

ABSTRAK 
 Kulit buah naga super merah (Hylocereus costaricencis) telah diteliti dan memiliki banyak manfaat. Beberapa kandungan yang terdapat di dalamnya adalah senyawa golongan flavonoid, vitamin C, lainnya. Komponen tersebut diuji dikatakan manfaat untuk menurunkan peroksidasi lipid. Dalam era ini, paparan sinar UV menginduksi macam hal negatif termasuk photo-aging melalui proses meningk...

BACKGROUND Photodynamic therapy using topical 5-aminolevulinic acid (ALA) has been successful in treating acne vulgaris, but sun avoidance for at least 48 hours after treatment is necessary due to the risk of post-treatment photosensitivity. Recently, a lower concentration of liposome-encapsulated 5-ALA was introduced to minimize this risk. OBJECTIVES To evaluate the efficacy and safety of li...

A set of 13 fatty acids was transformed into their phenacyl esters by reaction with phenacyl bromide in acetonitrile using 18-crown-6 as phase-transfer catalyst. Conditions for the RP-18 HPL chromatographic separation of most of the esters has been worked out. Using this standard the fatty acid spectra from skin surface sebum lipids of 17 test persons was taken after microwave-assisted hydrolys...

Pharmaceutical acne treatments are costly and have potentially severe side-effects. Adolescent acne is typically the result of clogged, infected, pilosebaceous follicles. Adults may experience fewer comedones and more inflammatory lesions. 1 Normally, sebum travels up the follicle to the skin surface. Hormones may increase sebum production and cause follicular cells to hyperproliferate and bloc...