Wiskott Aldrich Syndrome protein (WASP) has a unique regulatory role in sealing ring formation and bone resorption in osteoclasts. Here, using the TAT-transduction method, we show the possible role of WASP domain(s) in sealing ring formation and bone resorption. Transduction of TAT-fused full-length WASP peptide induced Arp2/3 complex formation, F-actin content, sealing ring formation and bone ...

INTRODUCTION This study aimed at evaluating the sealing properties of calcium-enriched mixture (CEM) compared to mineral trioxide aggregate (MTA) as a cervical barriers in intra-coronal bleaching. METHODS AND MATERIALS In this in vitro study, endodontic treatment was performed on 60 extracted human incisors and canines without canal calcification, caries, restorations, resorption or cracks. T...

PURPOSE The purpose of this study was to compare the sealing ability of temporary restorative materials at 24 hrs and 1 week. MATERIALS AND METHODS Endodontic access cavities were prepared in 56 extracted lower incisor-teeth and divided into 5 groups (n=10). Standard 5 mm deep access preparations were completed and root canals were prepared to size ISO #30 file. The access cavities were resto...

Introduction: Endodontic treatment failure is caused by the leakage of microorganisms and endotoxins, which leads to pathological lesions. Adequate seal of the root canal is essential to preventing recontamination and ensuring the long-term clinical success rate. Mineral trioxide aggregate (MTA) and calcium-enriched mixture cement (CEM) are common types of cement with adequate ...

background: apical leakage assessment is a way to compare the effi ciency of a fi lling material to seal the apical region of the tooth. many microleakage testing techniques have been introduced through the years, but there has been no agreement as to which technique gives the most accurate results. the aim of this study was to compare the accuracy of fl uid fi ltration and bacterial leakage te...